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Ligand · DGP

DGP · 2'-deoxyguanosine-5'-monophosphate

DGP, 2'-deoxyguanosine-5'-monophosphate (C10 H14 N5 O7 P, 347.2 g/mol), in the MolNFT structures on GenesisL1: bound in 12 records (10 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the…

Component
DGP
Formula
C10 H14 N5 O7 P
Class
ligand
Structures
12
PDB entries
10

Binding sites

DGP in 12 structures; the first of them:

  • 6TNH · Deoxyguanylosuccinate synthase (DgsS) quaternary structure with AMPPcP, dGMP, Asp… · DGP A405 · binds PHE12, GLY13, SER14, ASN40, ALA41, ILE121, ILE125, GLY126 and 13 more
  • 6V0L · PDGFR-b Promoter Forms a G-Vacancy Quadruplex that Can be Complemented by dGMP: Molecular… · DGP X101 · binds 3D11, DA2, DG7, DG8, DG11, DG14
  • 6YVP · Human histidine triad nucleotide-binding protein 2 (hHINT2) complexed with dGMP and… · DGP AAA201 · binds ILE55, PHE56, ILE59, LEU64, PHE78, ARG79, ASP80, VAL81 and 10 more
  • 7ODX · Cyanophage S-2L Succinoaminodeoxyadenylate synthetase (PurZ) bound to dGMP and dATP as an… · DGP A401 · binds TYR21, GLY22, SER23, ASN49, ALA50, HIS52, ALA128, PRO129 and 13 more
  • 8KA4 · Arabidopsis AP endonuclease ARP complex with 21bp THF-containing DNA · DGP B601 · binds VAL318, TRP337, SER338, CYS339, VAL341, HIS369, ASP370, THR371
  • 8SY6 · E. coli DNA-directed RNA polymerase transcription elongation complex bound the unnatural… · DGP T101 · binds DT28, LEU255, ASP256, ARG259, ALA261, THR262, A1
  • 8VAW · Magnesium catalyzed primer extension product with 14mer primer and mixed phosphorothioate… · DGP A203 · binds G4615, LCC1, LCC2
  • 8VAX · Cadmium catalyzed primer extension product with 14mer primer and mixed phosphorothioate… · DGP BBB101 · binds G4615, LCC1, LCC2
  • 6FKO · Deoxyguanylosuccinate synthase (dgss) quaternary structure with ATP, dgmp, hadacidin at… · DGP A402 · binds PHE12, SER14, ASN40, ALA41, ILE125, GLY126, SER127, THR128 and 7 more
  • 6FM1 · Deoxyguanylosuccinate synthase (dgss) quaternary structure with atpanddgmp at 2.3… · DGP A402 · binds PHE12, GLY13, SER14, ASN40, ALA41, ILE125, GLY126, SER127 and 9 more
  • 6TNH · Deoxyguanylosuccinate synthase (dgss) quaternary structure with amppcp, dgmp, asp… · DGP A405 · binds PHE12, GLY13, SER14, ASN40, ALA41, ILE125, GLY126, SER127 and 8 more
  • 7ODX · Cyanophage S-2L succinoaminodeoxyadenylate synthetase (purz) bound to dgmp and datp as an… · DGP A401 · binds TYR21, GLY22, SER23, ASN49, ALA50, GLY130, SER131, THR132 and 5 more

Residues it binds most

SER 14, THR 13, ILE 11, GLY 10, ARG 12, VAL 14, ALA 13, LEU 13, GLN 13, ASN 12 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • ACP · Phosphomethylphosphonic acid adenylate ester
  • ATP · Adenosine-5'-triphosphate
  • DTP · 2'-deoxyadenosine 5'-triphosphate
  • SO4 · Sulfate ion
  • ASP · Aspartic acid
  • HDA · Hadacidin
  • UTP · Uridine 5'-triphosphate
  • ZN · Zinc ion
  • CL · Chloride ion
  • PO4 · Phosphate ion
  • FLC · Citrate anion

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