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Ligand · BMP

BMP · 6-hydroxyuridine-5'-phosphate

BMP, 6-hydroxyuridine-5'-phosphate (C9 H13 N2 O10 P, 340.2 g/mol), in the MolNFT structures on GenesisL1: bound in 106 records (53 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands…

Component
BMP
Formula
C9 H13 N2 O10 P
Class
ligand
Structures
106
PDB entries
53

Binding sites

BMP in 106 structures; the first of them:

  • 1DQX · Crystal structure of orotidine 5'-phosphate decarboxylase complexed to 6-hydroxyuridine… · BMP A601 · binds SER35, ASP37, LYS59, HIS61, ASP91, LYS93, LEU150, GLU152 and 14 more
  • 1JJK · Selenomethionine Substitution of Orotidine-5'-monophosphate Decarboxylase from E. coli… · BMP A301 · binds ALA20, ASP22, LYS44, ASP71, LYS73, VAL129, LEU130, THR131 and 12 more
  • 1LOR · crystal structure of orotidine 5'-monophosphate complexed with BMP · BMP A2001 · binds ALA18, ASP20, LYS42, ASP70, LYS72, LEU123, GLU125, MET126 and 10 more
  • 1X1Z · Orotidine 5'-monophosphate decarboxylase (odcase) complexed with BMP (produced from… · BMP A301 · binds ALA18, ASP20, LYS42, ASP70, LYS72, LEU123, GLU125, MET126 and 13 more
  • 2ZZ1 · Snapshot of the reaction from 6-CN-UMP to BMP catalyzed by Orotidine Monophosphate… · BMP A301 · binds ALA18, ASP20, LYS42, ASP70, LYS72, LEU123, GLU125, MET126 and 13 more
  • 2ZZ7 · Orotidine Monophosphate Decarboxylase K72A mutant complexed with BMP (produced from… · BMP A301 · binds ALA18, ASP20, LYS42, ASP70, LEU123, GLU125, MET126, SER127 and 10 more
  • 3BGG · Crystal structure of Human Orotidine 5'-monophosphate Decarboxylase complexed with BMP · BMP A1000 · binds SER68, ASP70, LYS92, HIS94, ASP123, LYS125, GLU181, MET182 and 11 more
  • 3EWX · K314A mutant of human orotidyl-5'-monophosphate decarboxylase in complex with… · BMP A481 · binds SER257, ASP259, LYS281, HIS283, ASP312, GLU370, MET371, SER372 and 10 more
  • 3EX4 · human orotidyl-5'-monophosphate decarboxylase in complex with BMP · BMP A481 · binds SER257, ASP259, LYS281, HIS283, ASP312, LYS314, GLU370, MET371 and 11 more
  • 3LTP · Crystal structure of orotidine 5'-monophosphate decarboxylase from Methanobacterium… · BMP A229 · binds ALA18, ASP20, LYS42, ASP70, LYS72, LEU123, GLU125, MET126 and 13 more
  • 3LTS · Crystal structure of the mutant V182A,I199A of orotidine 5'-monophosphate decarboxylase… · BMP A229 · binds ALA18, ASP20, LYS42, ASP70, LYS72, LEU123, GLU125, MET126 and 14 more
  • 3LTY · Crystal structure of the mutant V182A,I218A of orotidine 5'-monophosphate decarboxylase… · BMP A229 · binds ALA18, ASP20, LYS42, ASP70, LYS72, LEU123, GLU125, MET126 and 13 more
  • 3LV5 · Crystal structure of the mutant I199E of orotidine 5'-monophosphate decarboxylase from… · BMP A229 · binds ALA18, ASP20, LYS42, ASP70, LYS72, LEU123, GLU125, MET126 and 13 more
  • 3LV6 · Crystal structure of the mutant I218F of orotidine 5'-monophosphate decarboxylase from… · BMP A229 · binds ALA18, ASP20, LYS42, ASP70, LYS72, LEU123, GLU125, MET126 and 13 more
  • 3M1Z · Crystal structure of the mutant V182A.V201A of orotidine 5'-monophosphate decarboxylase… · BMP A229 · binds ALA18, ASP20, LYS42, ASP70, LYS72, LEU123, GLU125, MET126 and 13 more

Residues it binds most

ASP 228, ILE 228, VAL 224, LYS 228, ALA 204, GLY 228, PRO 228, ARG 212, THR 208, GLN 220 (residue and the binding sites it lines).

Found with

  • GOL · Glycerol
  • SO4 · Sulfate ion
  • CL · Chloride ion
  • PRO · Proline
  • MG · Magnesium ion
  • EDO · 1,2-ethanediol
  • 6CN · 6-cyanouridine 5'-phosphate
  • NI · Nickel (II) ion
  • ACY · Acetic acid
  • POL · N-propanol

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