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Ligand · PRO

PRO · Proline

PRO, Proline (C5 H9 N O2, 115.1 g/mol), in the MolNFT structures on GenesisL1: bound in 102 records (102 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
PRO
Formula
C5 H9 N O2
Class
ligand
Structures
102
PDB entries
102

Binding sites

PRO in 102 structures; the first of them:

  • 4WN9 · Structure of the Nitrogenase MoFe Protein from Clostridium pasteurianum Pressurized with… · PRO B502 · binds TYR30, HIS59, PHE60, PHE178, VAL179, GLY180, ASP183, GLY410 and 2 more
  • 5DIS · Crystal structure of a CRM1-RanGTP-SPN1 export complex bound to a 113 amino acid… · PRO A1101 · binds GLU428, ASN495, TRP499, ILE539, SER542, ASN543, TYR546, MET583
  • 5F9Y · Crystal Structure of Prolyl-tRNA Synthetase from Cryptosporidium parvum complexed with… · PRO A700 · binds THR300, GLU302, ARG331, TRP348, GLU350, HIS352, PHE395, THR419 and 4 more
  • 5IFM · Human NONO (p54nrb) Homodimer · PRO A402 · binds LEU155, PRO156, GLN157, PHE218, ARG220, GLU250
  • 5O1O · Crystal structure of human aminoadipate semialdehyde synthase, saccharopine dehydrogenase… · PRO A1002 · binds ASP604, CYS633, GLY634, GLY635, THR724, ARG726
  • 5ORF · Structure of ovine serum albumin in P1 space group · PRO A604 · binds VAL575, ALA576, GLN579, ALA580
  • 5OTB · Structure of caprine serum albumin in P1 space group · PRO A602 · binds ALA209, LEU210, ALA212, TRP213, SER343, LEU346, LEU480, VAL481
  • 5TGA · Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound… · PRO 13404 · binds A2820, U2875, U2954, 8AN3403
  • 5U56 · Structure of Francisella tularensis heterodimeric SspA (MglA-SspA) · PRO A304 · binds TYR11, ILE52, TYR63, ARG64, LEU65, ASN100, GLN105
  • 5VAD · Crystal structure of human Prolyl-tRNA synthetase (PRS) in complex with inhibitor · PRO A1602 · binds THR1121, GLU1123, ARG1152, TRP1169, GLU1171, HIS1173, PHE1216, THR1240 and 4 more
  • 5WZE · The structure of Pseudomonas aeruginosa aminopeptidase PepP · PRO A504 · binds LEU242, HIS243, HIS350, HIS361, GLU384, ARG406, TRP88

Residues it binds most

GLU 120, HIS 92, TRP 95, ARG 129, THR 94, GLY 98, PHE 91, SER 95, LEU 61, TYR 51 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • CL · Chloride ion
  • GOL · Glycerol
  • EDO · 1,2-ethanediol
  • MG · Magnesium ion
  • SO4 · Sulfate ion
  • CA · Calcium ion
  • K · Potassium ion
  • FME · N-formylmethionine
  • NA · Sodium ion
  • SR · Strontium ion
  • PEG · Di(hydroxyethyl)ether

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