MolNFT v2 · #37309 · protein
Second Ca2+ binding domain of the Na,Ca-exchanger (NCX1)
2FWU · Sodium/calcium exchanger 1: “Second Ca2+ binding domain of the Na,Ca-exchanger (NCX1)”. Solution nmr at NOT, 1 ligand (CA), 1 pocket (best druggability 0.41). MolNFT v2 #37309 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 2FWU
- Type
- protein
- Length
- 157 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- NOT
- Source
- Canis lupus familiaris
- Molecule
- Sodium/calcium exchanger 1
- UniProt
- P23685
- Ligands
- CA
- Pockets
- 1 · best druggability 0.41
Structure
solution nmr · resolution NOT · 1 distinct chain · 4% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sodium/calcium exchanger 1 | protein | 157 | 4% helix, 32% strand | P23685 |
Ligands and binding sites
- CA · Calcium ion · metal · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 152 | 0.41 | 0.74 | 18 | empty |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P23685
- Elsewhere: RCSB PDB 2FWU · PDBe 2FWU · UniProt P23685
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