UniProt P23685
Sodium/calcium exchanger 1 (P23685)
Sodium/calcium exchanger 1 (UniProt P23685): 16 experimental structures and 1 predicted model on GenesisL1, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P23685
- Protein
- Sodium/calcium exchanger 1
- Experimental structures
- 16
- Predicted models
- 1
- Pockets
- 11 · 1 record with a druggable one
Structures
17 records of P23685 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2DPK | The Crystal Structure of the Primary Ca2+ Sensor of the Na+/Ca2+ Exchanger | x-ray diffraction | A | — | — |
| 2DPK | The crystal structure of the primary CA2+ sensor of the NA+/CA2+ exchanger | x-ray diffraction | A | — | — |
| 2FWS | First Ca2+ binding domain of the Na,Ca-exchanger (NCX1) | solution nmr | A | — | — |
| 2FWS | First CA2+ binding domain of the NA,CA-exchanger (NCX1) | solution nmr | A | — | — |
| 2FWU | Second Ca2+ binding domain of the Na,Ca-exchanger (NCX1) | solution nmr | A | — | — |
| 2FWU | Second CA2+ binding domain of the NA,CA-exchanger (NCX1) | solution nmr | A | — | — |
| 2QVK | The second Ca2+-binding domain of the Na+-Ca2+ exchanger is essential for regulation: crystal… | x-ray diffraction | A | — | — |
| 2QVK | The second CA2+-binding domain of the na+-CA2+ exchanger is essential for regulation: crystal… | x-ray diffraction | A | — | — |
| 2QVM | The second Ca2+-binding domain of the Na+-Ca2+ exchanger is essential for regulation: crystal… | x-ray diffraction | A | — | — |
| 2QVM | The second CA2+-binding domain of the na+-CA2+ exchanger is essential for regulation: crystal… | x-ray diffraction | A | — | — |
| 3GIN | Crystal structure of E454K-CBD1 | x-ray diffraction | A, B | — | — |
| 3GIN | Crystal structure of E454K-CBD1 | x-ray diffraction | A, B | — | — |
| 3US9 | Crystal Structure of the NCX1 Intracellular Tandem Calcium Binding Domains(CBD12) | x-ray diffraction | A | — | — |
| 3US9 | Crystal structure of the NCX1 intracellular tandem calcium binding DOMAINS(CBD12) | x-ray diffraction | A | — | — |
| 6BV7 | NMR structure of Sodium/Calcium Exchanger 1 (NCX1) Two-helix Bundle (THB) domain | solution nmr | A | — | — |
| 6BV7 | NMR structure of SODIUM/CALCIUM exchanger 1 (NCX1) two-helix bundle (thb) domain | solution nmr | A | — | — |
| P23685 | AlphaFold monomer V2.0 prediction for SODIUM/CALCIUM exchanger 1 (P23685) | predicted | A | — | 11 (best 0.78) |
Experiment against prediction
- 3GIN chain B against the predicted model P23685: TM-score 0.99, RMSD 0.50 Å
- 3GIN chain B against the predicted model P23685: TM-score 0.99, RMSD 0.50 Å
- 3GIN chain A against the predicted model P23685: TM-score 0.98, RMSD 0.75 Å
- 3GIN chain A against the predicted model P23685: TM-score 0.98, RMSD 0.75 Å
- 2QVM chain A against the predicted model P23685: TM-score 0.97, RMSD 0.75 Å
- 2QVM chain A against the predicted model P23685: TM-score 0.97, RMSD 0.75 Å
- 2DPK chain A against the predicted model P23685: TM-score 0.95, RMSD 1.43 Å
- 2DPK chain A against the predicted model P23685: TM-score 0.95, RMSD 1.43 Å
- 2QVK chain A against the predicted model P23685: TM-score 0.94, RMSD 1.38 Å
- 2QVK chain A against the predicted model P23685: TM-score 0.94, RMSD 1.38 Å
Elsewhere
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