MolNFT v2 · #22910 · protein
Crystallographic Identification of Ca2+ Coordination Sites in Synaptotagmin I C2B Domain
1TJX · similar to synaptotagminI/p65: “Crystallographic Identification of Ca2+ Coordination Sites in Synaptotagmin I C2B Domain”. X-ray diffraction at 1.04, 1 ligand (CA), 1 pocket (best druggability 0.45). MolNFT v2 #22910 on GenesisL1…
- PDB
- 1TJX
- Type
- protein
- Length
- 156 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.04
- Source
- Rattus norvegicus
- Molecule
- similar to synaptotagminI/p65
- UniProt
- P21707
- Ligands
- CA
- Pockets
- 1 · best druggability 0.45
Structure
x-ray diffraction · resolution 1.04 · 1 distinct chain · 19% helix, 44% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | similar to synaptotagminI/p65 | protein | 156 | 19% helix, 44% strand | P21707 |
Ligands and binding sites
- CA · Calcium ion · metal · 2 copies · chains A
- ACT · Acetate ion · additive · chains A
- GOL · Glycerol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 54 | 0.45 | 0.84 | 19 | GOL |
Compared structures
- 1TJX · Crystallographic identification of CA2+ coordination sites in synaptotagmin I C2B domain · the same entry in another collection · chain A against A, TM-score 1.00
- P21707 · AlphaFold monomer V2.0 prediction for synaptotagmin-1 (P21707) · a predicted model of the same protein · chain A against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P21707
- Elsewhere: RCSB PDB 1TJX · PDBe 1TJX · UniProt P21707
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