UniProt P21707
Synaptotagmin-1 (P21707)
Synaptotagmin-1 (UniProt P21707): 33 experimental structures on GenesisL1, 3 ligands bound, 13 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P21707
- Protein
- Synaptotagmin-1
- Experimental structures
- 33
- Predicted models
- 0
- Ligands
- 3
- Pockets
- 13 · 1 record with a druggable one
Structures
33 records of P21707 in the MolNFT archive: 33 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1BYN | Solution structure of the calcium-bound first C2-domain of synaptotagmin I | solution nmr | A | — | — |
| 1BYN | Solution structure of the calcium-bound first C2-domain of synaptotagmin I | solution nmr | A | — | — |
| 1K5W | Three-dimensional structure of the synaptotagmin 1 C2B-domain: synaptotagmin 1 as a phospholipid… | solution nmr | A | — | — |
| 1K5W | Three-dimensional structure of the synaptotagmin 1 C2B-domain: synaptotagmin 1 as a phospholipid… | solution nmr | A | — | — |
| 1RSY | Structure of the first C2-domain of synaptotagmin I: a novel CA2+(SLASH)PHOSPHOLIPID binding fold | x-ray diffraction | A | — | — |
| 1RSY | Structure of the first C2-domain of synaptotagmin I: a novel CA2+(SLASH)PHOSPHOLIPID binding fold | x-ray diffraction | A | — | — |
| 1TJM | Crystallographic Identification of Sr2+ Coordination Site in Synaptotagmin I C2B Domain | x-ray diffraction | A | — | — |
| 1TJM | Crystallographic identification of SR2+ coordination site in synaptotagmin I C2B domain | x-ray diffraction | A | — | — |
| 1TJX | Crystallographic Identification of Ca2+ Coordination Sites in Synaptotagmin I C2B Domain | x-ray diffraction | A | — | — |
| 1TJX | Crystallographic identification of CA2+ coordination sites in synaptotagmin I C2B domain | x-ray diffraction | A | — | — |
| 1UOV | Calcium binding domain C2B | x-ray diffraction | A | — | — |
| 1UOV | Calcium binding domain C2B | x-ray diffraction | A | — | — |
| 1UOW | Calcium binding domain C2B | x-ray diffraction | A | — | — |
| 1UOW | Calcium binding domain C2B | x-ray diffraction | A | — | — |
| 2YOA | Synaptotagmin-1 C2B domain with phosphoserine | x-ray diffraction | A, B | — | — |
| 2YOA | Synaptotagmin-1 C2B domain with phosphoserine | x-ray diffraction | A, B | — | — |
| 4WEE | High-resolution structure of Synaptotagmin 1 C2A | x-ray diffraction | A | — | — |
| 4WEE | High-resolution structure of synaptotagmin 1 C2A | x-ray diffraction | A | — | — |
| 5CCG | Structure of the CA2+-bound synaptotagmin-1 snare complex (long unit cell form) | x-ray diffraction | E, F, K | — | — |
| 5CCH | Structure of the Ca2+-bound synaptotagmin-1 SNARE complex (short unit cell form) | x-ray diffraction | E, F | CA | 3 (best 0.45) |
| 5CCH | Structure of the CA2+-bound synaptotagmin-1 snare complex (short unit cell form) | x-ray diffraction | E, F | — | — |
| 5CCI | Structure of the Mg2+-bound synaptotagmin-1 SNARE complex (short unit cell form) | x-ray diffraction | E, F | MG | 5 (best 0.48) |
| 5CCI | Structure of the MG2+-bound synaptotagmin-1 snare complex (short unit cell form) | x-ray diffraction | E, F | — | — |
| 5CCJ | Crystal structure of the quintuple mutant of the synaptotagmin-1 C2B domain | x-ray diffraction | A, B, C, D | SO4 | 5 (best 0.72) |
| 5CCJ | Crystal structure of the quintuple mutant of the synaptotagmin-1 C2B domain | x-ray diffraction | A, B, C, D | — | — |
| 5KJ7 | Structure of the CA2+-bound synaptotagmin-1 snare complex (long unit cell form) - from xfel… | x-ray diffraction | E, F, K | CA | — |
| 5KJ8 | Structure of the CA2+-bound synaptotagmin-1 snare complex (long unit cell form) - from synchrotron… | x-ray diffraction | E, F, K | CA | — |
| 5W5C | Crystal structure of the primed snare-complexin-synaptotagmin-1 C2AB complex | x-ray diffraction | F | — | — |
| 5W5D | Crystal structure of the primed SNARE-Complexin-Synaptotagmin-1 C2B complex | x-ray diffraction | F | — | — |
| 5W5D | Crystal structure of the primed snare-complexin-synaptotagmin-1 C2B complex | x-ray diffraction | F | — | — |
| 6CXW | Synaptotagmin 1 C2A BETA4 chimera with enhanced PIP2 binding function | x-ray diffraction | A | — | — |
| 6MTI | Synaptotagmin-1 C2A, C2B domains and snare-pin proteins (5CCI) individually docked into cryo-EM MAP… | electron microscopy | 1, 2, 3, 4, 5, 6 | MG | — |
| P21707 | AlphaFold monomer V2.0 prediction for synaptotagmin-1 (P21707) | — | — | — |
Ligands
Elsewhere
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