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Ligand · SEP

SEP · Phosphoserine

SEP, Phosphoserine (C3 H8 N O6 P, 185.1 g/mol), in the MolNFT structures on GenesisL1: bound in 5 records (5 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
SEP
Formula
C3 H8 N O6 P
Class
ligand
Structures
5
PDB entries
5

Binding sites

SEP in 5 structures; the first of them:

  • 5F7H · Human T-cell immunoglobulin and mucin domain protein 4 (hTIM-4) complex with phosphoserine · SEP B202 · binds SER41, ARG92, VAL95, GLY97, TRP98, PHE99, ASN100, ASP101 and 2 more
  • 6CZZ · Crystal structure of Arabidopsis thaliana phosphoserine aminotransferase isoform 1… · SEP A502 · binds ALA78, GLY79, TRP171, THR221, ILE222, LYS265, HIS396, ARG397 and 6 more
  • 6QU3 · Crystal Structure of Phosphofructokinase from Trypanosoma brucei in complex with an… · SEP A1004 · binds TYR61, HIS236, PHE278, ARG418, ARG435, VAL436, ASP438
  • 7S0P · Crystal structure of Porcine Factor VIII C2 Domain Bound to Phosphatidylserine · SEP M2401 · binds GLN2213, GLY2214, ASN2217, GLN2246, VAL2248, LYS2249, SER2289, SER2290 and 1 more
  • 8JD6 · Cryo-EM structure of Gi1-bound metabotropic glutamate receptor mGlu4 · SEP S1002 · binds LYS74, ARG78, SER157, GLY158, SER159, ALA180, SER181, THR182 and 7 more

Residues it binds most

ARG 14, LYS 13, SER 9, GLY 13, ASN 11, THR 6, TRP 10, ASP 9, HIS 5, TYR 8 (residue and the binding sites it lines).

Found with

  • BK0 · N-(3-chlorophenyl)pyridine-2-carboxamide
  • JJ5 · 1-[(3,4-dichlorophenyl)methyl]-7~{H}-pyrrolo[3,2-c]pyridin-4-one
  • PLP · Pyridoxal-5'-phosphate
  • CA · Calcium ion
  • NA · Sodium ion
  • CIT · Citric acid
  • GOL · Glycerol

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