MolNFT v1 · #22904 · protein

Crystallographic identification of CA2+ coordination sites in synaptotagmin I C2B domain

1TJX · Similar to SYNAPTOTAGMINI/P65: “Crystallographic identification of CA2+ coordination sites in synaptotagmin I C2B domain”. X-ray diffraction, 1 ligand (CA), 1 pocket (best druggability 0.45). MolNFT v1 #22904 on GenesisL1: 3D…

PDB: 1TJX
Type: protein
Length: 156 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Similar to SYNAPTOTAGMINI/P65
UniProt: P21707
Ligands: CA
Pockets: 1 · best druggability 0.45

Structure

x-ray diffraction · 1 distinct chain · 19% helix, 44% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Similar to SYNAPTOTAGMINI/P65	protein	156	19% helix, 44% strand	P21707

Ligands and binding sites

CA · Calcium ion · metal · 2 copies · chains A
ACT · Acetate ion · additive · chains A
GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	54	0.45	0.84	19	GOL

Compared structures

1TJX · Crystallographic Identification of Ca2+ Coordination Sites in Synaptotagmin I C2B Domain · the same entry in another collection · chain A against A, TM-score 1.00
P21707 · AlphaFold monomer V2.0 prediction for synaptotagmin-1 (P21707) · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P21707
Elsewhere: RCSB PDB 1TJX · PDBe 1TJX · UniProt P21707

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.