MolNFT v2 · #196522 · protein
Integrin alpha IIB beta3 complex with BMS4-3
7UDH: “Integrin alpha IIB beta3 complex with BMS4-3”. X-ray diffraction at 1.99999, 8 ligands (MWO, NAG, MAN). MolNFT v2 #196522 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7UDH
- Type
- protein
- Length
- 2,702 residues
- Chains
- 8
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.99999
- Source
- Homo sapiens; Mus musculus
- UniProt
- P08514, P05106
- Ligands
- MWO, NAG, MAN, BMA, CA, MN, SO4, CL
Structure
x-ray diffraction · resolution 1.99999 · 7 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 454 | — | P08514 |
| B | — | protein | 466 | — | P05106 |
| C | — | protein | 453 | — | P08514 |
| D | — | protein | 471 | — | P05106 |
| E | — | protein | 214 | — | — |
| F, L | — | protein | 214 | — | — |
| H | — | protein | 216 | — | — |
Ligands and binding sites
- MWO · (4-{[(5S)-3-(piperidin-4-yl)-4,5-dihydro-1,2-oxazol-5-yl]methyl}piperazin-1-yl)acetic acid · ligand · 2 copies · chains A, B, C, D
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 10 copies · chains A, B, C, D
- MAN · alpha-D-mannopyranose · sugar · 4 copies · chains A, C
- BMA · beta-D-mannopyranose · sugar · 2 copies
- CA · Calcium ion · metal · 8 copies · chains A, C
- MN · Manganese (II) ion · metal · 6 copies · chains B, D
- SO4 · Sulfate ion · ion · 9 copies · chains A, C, L
- CL · Chloride ion · ion · 3 copies · chains C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7UDH · Integrin ALAPHIIBBETA3 complex with BMS4-3 · the same entry in another collection · chain L against L, TM-score 1.00
- P08514 · AlphaFold monomer V2.0 prediction for integrin alpha-iib (P08514) · a predicted model of the same protein · chain C against A, TM-score 1.00
- P05106 · AlphaFold monomer V2.0 prediction for integrin beta-3 (P05106) · a predicted model of the same protein · chain B against A, TM-score 0.90
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P08514
- Every structure of UniProt P05106
- Elsewhere: RCSB PDB 7UDH · PDBe 7UDH · UniProt P08514 · UniProt P05106
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