MolNFT v2 · #183410 · protein + DNA
Human PrimPol misinserting dATP opposite the 8-oxoguanine lesion (3'-end base of the primer strand is 2',3'-dideoxy-terminated).
7JKL: “Human PrimPol misinserting dATP opposite the 8-oxoguanine lesion (3'-end base of the primer strand is…”. X-ray diffraction at 2.384, 2 ligands (DTP, CA). MolNFT v2 #183410 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 7JKL
- Type
- protein + DNA
- Length
- 576 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.384
- Source
- Homo sapiens; SYNTHETIC CONSTRUCT
- UniProt
- Q96LW4
- Ligands
- DTP, CA
Structure
x-ray diffraction · resolution 2.384 · 5 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 269 | — | Q96LW4 |
| C, G | — | dna | 16 | — | — |
| D | — | dna | 13 | — | — |
| B | — | protein | 251 | — | Q96LW4 |
| H | — | dna | 11 | — | — |
Ligands and binding sites
- DTP · 2'-deoxyadenosine 5'-triphosphate · ligand · 2 copies · chains A, C, D, B, G, H
- CA · Calcium ion · metal · 3 copies · chains A, B, H
- GOL · Glycerol · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7JKL · Human primpol misinserting datp opposite the 8-oxoguanine lesion (3'- end base of the… · the same entry in another collection · chain H against H, TM-score 1.00
- Q96LW4 · AlphaFold monomer V2.0 prediction for DNA-directed PRIMASE/POLYMERASE protein (Q96LW4) · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q96LW4
- Elsewhere: RCSB PDB 7JKL · PDBe 7JKL · UniProt Q96LW4
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.