MolNFT v2 · #158839 · protein + RNA
Crystal structure of the Thermus thermophilus 70S ribosome in complex with a short substrate mimic CC-Pmn and bound to mRNA and P-site tRNA at 3.7A resolution
6N9E: “Crystal structure of the Thermus thermophilus 70S ribosome in complex with a short substrate mimic CC-Pmn and…”. X-ray diffraction at 3.7, 3 ligands (SF4, MG, ZN). MolNFT v2 #158839 on GenesisL1: 3D structure, binding sites and…
- PDB
- 6N9E
- Type
- protein + RNA
- Length
- 20,651 residues
- Chains
- 110
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 3.7
- Source
- Escherichia coli; Thermus thermophilus; SYNTHETIC CONSTRUCT
- UniProt
- Q56435, Q72IA7, P60493, P60494, Q72I12, P74909, Q72JR0, P80339, Q72GW3, P80340, P80374, P80375, P62654, P17293, P62655, P24320, P80378, P62238, P0DOY7, P62659, P62612
- Ligands
- SF4, MG, ZN
Structure
x-ray diffraction · resolution 3.7 · 60 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| 1A | — | rna | 2871 | — | — |
| 1B, 2B | — | rna | 120 | — | — |
| 1D, 2D | — | protein | 275 | — | — |
| 1E, 2E | — | protein | 204 | — | — |
| 1F, 2F | — | protein | 202 | — | — |
| 1G, 2G | — | protein | 181 | — | — |
| 1H, 2H | — | protein | 174 | — | — |
| 1I, 2I | — | protein | 146 | — | — |
| 1N, 2N | — | protein | 140 | — | — |
| 1O, 2O | — | protein | 122 | — | — |
| 1P, 2P | — | protein | 149 | — | — |
| 1Q, 2Q | — | protein | 141 | — | — |
| 1R, 2R | — | protein | 118 | — | — |
| 1S, 2S | — | protein | 110 | — | — |
| 1T, 2T | — | protein | 131 | — | — |
| 1U, 2U | — | protein | 116 | — | — |
| 1V, 2V | — | protein | 101 | — | — |
| 1W, 2W | — | protein | 112 | — | — |
| 1X, 2X | — | protein | 95 | — | — |
| 1Y, 2Y | — | protein | 107 | — | Q56435 |
| 1Z | — | protein | 154 | — | Q72IA7 |
| 10, 20 | — | protein | 83 | — | P60493 |
| 11, 21 | — | protein | 97 | — | P60494 |
| 12, 22 | — | protein | 70 | — | Q72I12 |
| 13, 23 | — | protein | 59 | — | P74909 |
| 14, 24 | — | protein | 69 | — | Q72JR0 |
| 15, 25 | — | protein | 59 | — | P80339 |
| 16, 26 | — | protein | 53 | — | Q72GW3 |
| 17, 27 | — | protein | 48 | — | P80340 |
| 18, 28 | — | protein | 64 | — | — |
| 19, 29 | — | protein | 37 | — | — |
| 1a | — | rna | 1499 | — | — |
| 1b, 2b | — | protein | 231 | — | — |
| 1c, 2c | — | protein | 206 | — | — |
| 1d, 2d | — | protein | 208 | — | — |
| 1e, 2e | — | protein | 148 | — | — |
| 1f, 2f | — | protein | 100 | — | — |
| 1g, 2g | — | protein | 155 | — | — |
| 1h, 2h | — | protein | 137 | — | — |
| 1i, 2i | — | protein | 127 | — | P80374 |
| 1j | — | protein | 97 | — | P80375 |
| 1k, 2k | — | protein | 114 | — | P62654 |
| 1l, 2l | — | protein | 122 | — | P17293 |
| 1m | — | protein | 123 | — | P62655 |
| 1n, 2n | — | protein | 60 | — | P24320 |
| 1o, 2o | — | protein | 88 | — | P80378 |
| 1p, 2p | — | protein | 82 | — | P62238 |
| 1q, 2q | — | protein | 99 | — | P0DOY7 |
| 1r, 2r | — | protein | 68 | — | P62659 |
| 1s, 2s | — | protein | 83 | — | — |
| 1t, 2t | — | protein | 96 | — | — |
| 1u, 2u | — | protein | 23 | — | P62612 |
| 1v, 2v | — | rna | 5 | — | — |
| 1w, 2w | — | rna | 2 | — | — |
| 1x, 2x | — | rna | 76 | — | — |
| 2A | — | rna | 2800 | — | — |
| 2Z | — | protein | 160 | — | Q72IA7 |
| 2a | — | rna | 1503 | — | — |
| 2j | — | protein | 96 | — | P80375 |
| 2m | — | protein | 122 | — | P62655 |
Ligands and binding sites
- SF4 · Iron/sulfur cluster · ligand · 2 copies · chains 1d, 2d
- MG · Magnesium ion · metal · 1156 copies · chains 1A, 1D, 1P, 1F, 13, 1V, 1B, 1R, 1Y, 1T, 1X, 1E, 1U, 18, 1N, 1a, 1S, 1W, 10, 15, 16, 17, 1t, 1q, 1u, 1h, 1l, 1i, 1d, 1m, 1r, 1x, 2A, 2P, 2F, 2D, 28, 2W, 2X, 2a, 2E, 2R, 2U, 2V, 2B, 2T, 2O, 2Q, 25, 2Y, 20, 21, 23, 2i, 2c, 2k, 2p, 2d, 2f, 2l, 2r
- ZN · Zinc ion · metal · 12 copies · chains 1Y, 14, 15, 16, 19, 1n, 2Y, 24, 25, 26, 29, 2n
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- P62238 · AlphaFold monomer V2.0 prediction for 30S ribosomal protein S16 (P62238) · a predicted model of the same protein · chain 1p against A, TM-score 0.97
- P80378 · AlphaFold monomer V2.0 prediction for 30S ribosomal protein S15 (P80378) · a predicted model of the same protein · chain 1o against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q56435
- Every structure of UniProt Q72IA7
- Every structure of UniProt P60493
- Every structure of UniProt P60494
- Every structure of UniProt Q72I12
- Every structure of UniProt P74909
- Every structure of UniProt Q72JR0
- Every structure of UniProt P80339
- Every structure of UniProt Q72GW3
- Every structure of UniProt P80340
- Every structure of UniProt P80374
- Every structure of UniProt P80375
- Every structure of UniProt P62654
- Every structure of UniProt P17293
- Every structure of UniProt P62655
- Every structure of UniProt P24320
- Every structure of UniProt P80378
- Every structure of UniProt P62238
- Every structure of UniProt P0DOY7
- Every structure of UniProt P62659
- Every structure of UniProt P62612
- Elsewhere: RCSB PDB 6N9E · PDBe 6N9E · UniProt Q56435 · UniProt Q72IA7 · UniProt P60493 · UniProt P60494 · UniProt Q72I12 · UniProt P74909 · UniProt Q72JR0 · UniProt P80339 · UniProt Q72GW3 · UniProt P80340 · UniProt P80374 · UniProt P80375 · UniProt P62654 · UniProt P17293 · UniProt P62655 · UniProt P24320 · UniProt P80378 · UniProt P62238 · UniProt P0DOY7 · UniProt P62659 · UniProt P62612
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