UniProt Q72GW3
50S ribosomal protein L33 (Q72GW3)
50S ribosomal protein L33 (UniProt Q72GW3): 27 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 22 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q72GW3
- Protein
- 50S ribosomal protein L33
- Experimental structures
- 27
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 22 · 12 records with a druggable one
Structures
28 records of Q72GW3 in the MolNFT archive: 27 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4V63 | Structural basis for translation termination on the 70S ribosome. | x-ray diffraction | B6, D6 | — | — |
| 4V67 | Crystal structure of a translation termination complex formed with release factor RF2. | x-ray diffraction | B6, D6 | — | — |
| 4V7P | Recognition of the amber stop codon by release factor RF1. | x-ray diffraction | B3, C3 | — | — |
| 4V83 | Crystal structure of a complex containing domain 3 from the PSIV IGR IRES RNA bound to the 70S… | x-ray diffraction | B3, D3 | — | — |
| 4V84 | Crystal structure of a complex containing domain 3 of CrPV IGR IRES RNA bound to the 70S ribosome. | x-ray diffraction | B3, D3 | — | — |
| 4V9J | 70S ribosome translocation intermediate GDPNP-II containing elongation factor EFG/GDPNP, mRNA, and… | x-ray diffraction | B6, D6 | — | — |
| 4V9K | 70S ribosome translocation intermediate GDPNP-I containing elongation factor EFG/GDPNP, mRNA, and… | x-ray diffraction | B6, D6 | — | — |
| 4V9L | 70S Ribosome translocation intermediate FA-3.6A containing elongation factor EFG/FUSIDIC ACID/GDP… | x-ray diffraction | B6, D6 | — | — |
| 4V9M | 70S Ribosome translocation intermediate FA-4.2A containing elongation factor EFG/FUSIDIC ACID/GDP… | x-ray diffraction | B6, D6 | — | — |
| 4V9N | Crystal structure of the 70S ribosome bound with the Q253P mutant of release factor RF2. | x-ray diffraction | B6, D6 | — | — |
| 4V9Q | Crystal Structure of Blasticidin S Bound to Thermus Thermophilus 70S Ribosome. | x-ray diffraction | A3, C3 | — | — |
| 4W29 | 70S ribosome translocation intermediate containing elongation factor EFG/GDP/fusidic acid, mRNA… | x-ray diffraction | B6, D6 | — | — |
| 4XEJ | IRES bound to bacterial Ribosome | x-ray diffraction | AL33, BL33 | — | 1 (best 0.87) |
| 4ZER | Crystal structure of the Onc112 antimicrobial peptide bound to the Thermus thermophilus 70S ribosome | x-ray diffraction | 16, 26 | ZN, MG | 2 (best 0.88) |
| 5J4D | E. coli release factor 1 bound to the 70S ribosome in response to a pseudouridylated stop codon | x-ray diffraction | DA, IC | MG, ZN | 2 (best 0.86) |
| 5V8I | Thermus thermophilus 70S ribosome lacking ribosomal protein uS17 | x-ray diffraction | 16, 26 | ZN, MG | 2 (best 0.88) |
| 5VPO | The 70S P-site ASL SufA6 complex | x-ray diffraction | R6, Y6 | — | 2 (best 0.88) |
| 6B4V | Antibiotic blasticidin S and E. coli release factor 1 bound to the 70S ribosome | x-ray diffraction | DA, HC | ZN, MG | 2 (best 0.86) |
| 6BOH | Antibiotic blasticidin S and E. coli release factor 1 (containing deletion 302-304) bound to the… | x-ray diffraction | DA, IC | ZN, MG | 2 (best 0.87) |
| 6BOK | E. coli release factor 1 (containing deletion 302-304) bound to the 70S ribosome | x-ray diffraction | DA, GC | ZN, MG | — |
| 6C5L | Conformation of methylated GGQ in the Peptidyl Transferase Center during translation termination… | x-ray diffraction | B6, D6 | — | 2 (best 0.89) |
| 6CFJ | Crystal structure of the Thermus thermophilus 70S ribosome in complex with histidyl-CAM and bound… | x-ray diffraction | 16, 26 | MG, ZN | 2 (best 0.88) |
| 6CFK | Crystal structure of the Thermus thermophilus 70S ribosome in complex with D-histidyl-CAM and bound… | x-ray diffraction | 16, 26 | ZN, MG | 2 (best 0.87) |
| 6CFL | Crystal structure of the Thermus thermophilus 70S ribosome in complex with lysyl-CAM and bound to… | x-ray diffraction | 16, 26 | MG, ZN | 2 (best 0.86) |
| 6N1D | X-ray Crystal complex showing Spontaneous Ribosomal Translocation of mRNA and tRNAs into a Chimeric… | x-ray diffraction | AL33, BL33 | MG | 1 (best 0.86) |
| 6N9E | Crystal structure of the Thermus thermophilus 70S ribosome in complex with a short substrate mimic… | x-ray diffraction | 16, 26 | MG, ZN | — |
| 6N9F | Crystal structure of the Thermus thermophilus 70S ribosome in complex with a short substrate mimic… | x-ray diffraction | 16, 26 | MG, ZN | — |
| Q72GW3 | AlphaFold monomer V2.0 prediction for 50S ribosomal protein L33 (Q72GW3) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6CFJ chain 16 against the predicted model Q72GW3: TM-score 0.88, RMSD 0.97 Å
- 6N9E chain 16 against the predicted model Q72GW3: TM-score 0.88, RMSD 0.99 Å
- 5J4D chain DA against the predicted model Q72GW3: TM-score 0.88, RMSD 1.04 Å
- 6CFJ chain 26 against the predicted model Q72GW3: TM-score 0.88, RMSD 1.03 Å
- 6CFL chain 26 against the predicted model Q72GW3: TM-score 0.88, RMSD 1.02 Å
- 6N9F chain 16 against the predicted model Q72GW3: TM-score 0.88, RMSD 0.99 Å
- 6CFL chain 16 against the predicted model Q72GW3: TM-score 0.88, RMSD 1.02 Å
- 4ZER chain 16 against the predicted model Q72GW3: TM-score 0.88, RMSD 1.00 Å
- 5V8I chain 16 against the predicted model Q72GW3: TM-score 0.88, RMSD 1.01 Å
- 6CFK chain 16 against the predicted model Q72GW3: TM-score 0.87, RMSD 1.03 Å
Elsewhere
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