MolNFT v2 · #15623 · protein
Crystal structure of the catalytic subunit of human protein kinase CK2
1NA7 · Casein kinase II, alpha chain: “Crystal structure of the catalytic subunit of human protein kinase CK2”. X-ray diffraction at 2.4, 2 pockets (best druggability 0.65). MolNFT v2 #15623 on GenesisL1: 3D structure, binding sites and…
- PDB
- 1NA7
- Type
- protein
- Length
- 326 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.4
- Source
- Homo sapiens
- Molecule
- Casein kinase II, alpha chain
- EC
- 2.7.1.37
- UniProt
- P68400
- Pockets
- 2 · best druggability 0.65
Structure
x-ray diffraction · resolution 2.4 · 1 distinct chain · 38% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Casein kinase II, alpha chain (EC 2.7.1.37) | protein | 326 | 38% helix, 15% strand | P68400 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 326 | 0.65 | 0.80 | 40 | empty |
| 2 | 64 | 0.33 | 0.76 | 13 | empty |
Compared structures
- 1NA7 · Crystal structure of the catalytic subunit of human protein kinase CK2 · the same entry in another collection · chain A against A, TM-score 1.00
- P68400 · AlphaFold monomer V2.0 prediction for casein kinase II subunit alpha (P68400) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P68400
- Elsewhere: RCSB PDB 1NA7 · PDBe 1NA7 · UniProt P68400
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