MolNFT v1 · #15615 · protein
Crystal structure of the catalytic subunit of human protein kinase CK2
1NA7 · Casein kinase II, alpha chain: “Crystal structure of the catalytic subunit of human protein kinase CK2”. X-ray diffraction, 2 pockets (best druggability 0.65). MolNFT v1 #15615 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 1NA7
- Type
- protein
- Length
- 326 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Casein kinase II, alpha chain
- EC
- 2.7.1.37
- UniProt
- P68400
- Pockets
- 2 · best druggability 0.65
Structure
x-ray diffraction · 1 distinct chain · 38% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Casein kinase II, alpha chain (EC 2.7.1.37) | protein | 326 | 38% helix, 15% strand | P68400 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 326 | 0.65 | 0.80 | 40 | empty |
| 2 | 64 | 0.33 | 0.76 | 13 | empty |
Compared structures
- 1NA7 · Crystal structure of the catalytic subunit of human protein kinase CK2 · the same entry in another collection · chain A against A, TM-score 1.00
- P68400 · AlphaFold monomer V2.0 prediction for casein kinase II subunit alpha (P68400) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P68400
- Elsewhere: RCSB PDB 1NA7 · PDBe 1NA7 · UniProt P68400
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