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MolNFT v2 · #152621 · protein + DNA

Cryo-EM structure of the human INO80 complex bound to nucleosome

6HTS: “Cryo-EM structure of the human INO80 complex bound to nucleosome”. Electron microscopy at 4.8, 2 ligands (ADP, ZN). MolNFT v2 #152621 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6HTS
Type
protein + DNA
Length
4,753 residues
Chains
19
Method
electron microscopy
Collection
MolNFT v2 / PDB Bank
Contract
0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner
0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution
4.8
Source
Homo sapiens; SYNTHETIC CONSTRUCT
UniProt
Q9Y265, Q9Y230, Q9ULG1, Q9H9F9, P68431, P62805, P04908, P06899, Q9C086
Ligands
ADP, ZN

Structure

electron microscopy · resolution 4.8 · 18 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein434—Q9Y265
B—protein429—Q9Y230
C—protein437—Q9Y265
D, F—protein434—Q9Y230
E—protein443—Q9Y265
G—protein680—Q9ULG1
H—protein326—Q9H9F9
I—protein96—P68431
J—protein82—P62805
K—protein106—P04908
L—protein96—P06899
M—protein99—P68431
N—protein86—P62805
O—protein105—P04908
P—protein94—P06899
R—protein72—Q9C086
X—dna150——
Y—dna150——

Ligands and binding sites

  • ADP · Adenosine-5'-diphosphate · ligand · 6 copies · chains A, B, C, D, E, F
  • ZN · Zinc ion · metal · chains R

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6HTS · Cryo-EM structure of the human INO80 complex bound to nucleosome · the same entry in another collection · chain J against J, TM-score 1.00

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