UniProt P04908
Histone H2A type 1-B/E (P04908)
Histone H2A type 1-B/E (UniProt P04908), EC 2.3.2.23, 2.3.2.24: 306 experimental structures and 1 predicted model on GenesisL1, 13 ligands bound, 938 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P04908
- Protein
- Histone H2A type 1-B/E
- EC
- 2.3.2.23, 2.3.2.24, 2.3.2.27
- Experimental structures
- 306
- Predicted models
- 1
- Ligands
- 13
- Pockets
- 938 · 94 records with a druggable one
Structures
307 records of P04908 in the MolNFT archive: 306 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2RVQ | Solution structure of the isolated histone H2A-H2B heterodimer | solution nmr | C | — | — |
| 2RVQ | Solution structure of the isolated histone H2A-H2B heterodimer | solution nmr | C | — | — |
| 3A6N | The nucleosome containing a testis-specific histone variant, human H3T | x-ray diffraction | C, G | — | — |
| 3A6N | The nucleosome containing a testis-specific histone variant, human H3T | x-ray diffraction | C, G | — | — |
| 3AFA | The human nucleosome structure | x-ray diffraction | C, G | — | — |
| 3AFA | The human nucleosome structure | x-ray diffraction | C, G | — | — |
| 3AN2 | The structure of the centromeric nucleosome containing CENP-A | x-ray diffraction | C, G | — | — |
| 3AN2 | The structure of the centromeric nucleosome containing cenp-a | x-ray diffraction | C, G | — | — |
| 3AV1 | The human nucleosome structure containing the histone variant H3.2 | x-ray diffraction | C, G | — | — |
| 3AV1 | The human nucleosome structure containing the histone variant H3.2 | x-ray diffraction | C, G | — | — |
| 3AV2 | The human nucleosome structure containing the histone variant H3.3 | x-ray diffraction | C, G | — | — |
| 3AV2 | The human nucleosome structure containing the histone variant H3.3 | x-ray diffraction | C, G | — | — |
| 3AYW | Crystal Structure of Human Nucleosome Core Particle Containing H3K56Q mutation | x-ray diffraction | C, G | — | — |
| 3AYW | Crystal structure of human nucleosome core particle containing H3K56Q mutation | x-ray diffraction | C, G | — | — |
| 3AZE | Crystal Structure of Human Nucleosome Core Particle Containing H3K64Q mutation | x-ray diffraction | C, G | — | — |
| 3AZE | Crystal structure of human nucleosome core particle containing H3K64Q mutation | x-ray diffraction | C, G | — | — |
| 3AZF | Crystal Structure of Human Nucleosome Core Particle Containing H3K79Q mutation | x-ray diffraction | C, G | — | — |
| 3AZF | Crystal structure of human nucleosome core particle containing H3K79Q mutation | x-ray diffraction | C, G | — | — |
| 3AZG | Crystal Structure of Human Nucleosome Core Particle Containing H3K115Q mutation | x-ray diffraction | C, G | — | — |
| 3AZG | Crystal structure of human nucleosome core particle containing H3K115Q mutation | x-ray diffraction | C, G | — | — |
| 3AZH | Crystal Structure of Human Nucleosome Core Particle Containing H3K122Q mutation | x-ray diffraction | C, G | — | — |
| 3AZH | Crystal structure of human nucleosome core particle containing H3K122Q mutation | x-ray diffraction | C, G | — | — |
| 3AZI | Crystal Structure of Human Nucleosome Core Particle Containing H4K31Q mutation | x-ray diffraction | C, G | — | — |
| 3AZI | Crystal structure of human nucleosome core particle containing H4K31Q mutation | x-ray diffraction | C, G | — | — |
| 3AZJ | Crystal Structure of Human Nucleosome Core Particle Containing H4K44Q mutation | x-ray diffraction | C, G | — | — |
| 3AZJ | Crystal structure of human nucleosome core particle containing H4K44Q mutation | x-ray diffraction | C, G | — | — |
| 3AZK | Crystal Structure of Human Nucleosome Core Particle Containing H4K59Q mutation | x-ray diffraction | C, G | — | — |
| 3AZK | Crystal structure of human nucleosome core particle containing H4K59Q mutation | x-ray diffraction | C, G | — | — |
| 3AZL | Crystal Structure of Human Nucleosome Core Particle Containing H4K77Q mutation | x-ray diffraction | C, G | — | — |
| 3AZL | Crystal structure of human nucleosome core particle containing H4K77Q mutation | x-ray diffraction | C, G | — | — |
| 3AZM | Crystal Structure of Human Nucleosome Core Particle Containing H4K79Q mutation | x-ray diffraction | C, G | — | — |
| 3AZM | Crystal structure of human nucleosome core particle containing H4K79Q mutation | x-ray diffraction | C, G | — | — |
| 3AZN | Crystal Structure of Human Nucleosome Core Particle Containing H4K91Q mutation | x-ray diffraction | C, G | — | — |
| 3AZN | Crystal structure of human nucleosome core particle containing H4K91Q mutation | x-ray diffraction | C, G | — | — |
| 3W96 | Crystal Structure of Human Nucleosome Core Particle lacking H2A N-terminal region | x-ray diffraction | C, G | — | — |
| 3W96 | Crystal structure of human nucleosome core particle lacking H2A N- terminal region | x-ray diffraction | C, G | — | — |
| 3W97 | Crystal Structure of Human Nucleosome Core Particle lacking H2B N-terminal region | x-ray diffraction | C, G | — | — |
| 3W97 | Crystal structure of human nucleosome core particle lacking H2B N- terminal region | x-ray diffraction | C, G | — | — |
| 3W98 | Crystal Structure of Human Nucleosome Core Particle lacking H3.1 N-terminal region | x-ray diffraction | C, G | — | — |
| 3W98 | Crystal structure of human nucleosome core particle lacking H3.1 N- terminal region | x-ray diffraction | C, G | — | — |
| 3W99 | Crystal Structure of Human Nucleosome Core Particle lacking H4 N-terminal region | x-ray diffraction | C, G | — | — |
| 3W99 | Crystal structure of human nucleosome core particle lacking H4 N- terminal region | x-ray diffraction | C, G | — | — |
| 3WKJ | The nucleosome containing human TSH2B | x-ray diffraction | C, G | — | — |
| 3WKJ | The nucleosome containing human TSH2B | x-ray diffraction | C, G | — | — |
| 3WTP | Crystal Structure of the heterotypic nucleosome containing human CENP-A and H3.3 | x-ray diffraction | C, G | — | — |
| 3WTP | Crystal structure of the heterotypic nucleosome containing human cenp- a and H3.3 | x-ray diffraction | C, G | — | — |
| 3X1S | Crystal structure of the nucleosome core particle | x-ray diffraction | C, G | — | — |
| 3X1S | Crystal structure of the nucleosome core particle | x-ray diffraction | C, G | — | — |
| 3X1V | Crystal structure of nucleosome core particle in the presence of histone variant involved in… | x-ray diffraction | C, G | — | — |
| 3X1V | Crystal structure of nucleosome core particle in the presence of histone variant involved in… | x-ray diffraction | C, G | — | — |
| 4YM5 | Crystal structure of the human nucleosome containing 6-4PP (inside) | x-ray diffraction | C, G | — | — |
| 4YM5 | Crystal structure of the human nucleosome containing 6-4PP (inside) | x-ray diffraction | C, G | — | — |
| 4YM6 | Crystal structure of the human nucleosome containing 6-4PP (outside) | x-ray diffraction | C, G | — | — |
| 4YM6 | Crystal structure of the human nucleosome containing 6-4PP (outside) | x-ray diffraction | C, G | — | — |
| 4Z5T | The nucleosome containing human H3.5 | x-ray diffraction | C, G | — | — |
| 4Z5T | The nucleosome containing human H3.5 | x-ray diffraction | C, G | — | — |
| 5AV5 | human nucleosome core particle | x-ray diffraction | C, G | — | 12 (best 0.78) |
| 5AV5 | Human nucleosome core particle | x-ray diffraction | C, G | — | — |
| 5AV6 | human nucleosome core particle | x-ray diffraction | C, G | — | — |
| 5AV6 | Human nucleosome core particle | x-ray diffraction | C, G | — | — |
247 records more on the page itself.
Ligands
- CL · Chloride ion · in 19 records
- CA · Calcium ion · in 9 records
- PTD · Pentanedial · in 5 records
- RUD · [ethane6-3-(p-tolyl)propanoic acid]Ru(1,3,5-triaza-7-phosphaadamantane)Cl2 · in 5 records
- K · Potassium ion · in 3 records
- ZN · Zinc ion · in 3 records
- MN · Manganese (II) ion · in 2 records
- NA · Sodium ion · in 2 records
- D0X · [ru(eta(6)-P-cymene)cl-2(pta) · in 1 record
- MG · Magnesium ion · in 1 record
- RRK · (1R,2R)-1,2-diphenylethane-1,2-diamine · in 1 record
- RSK · (1S,2R)-1,2-diphenylethane-1,2-diamine · in 1 record
- SSK · (1S,2S)-1,2-diphenylethane-1,2-diamine · in 1 record
Experiment against prediction
- 3AZJ chain G against the predicted model P04908: TM-score 0.97, RMSD 0.64 Å
- 3AZJ chain G against the predicted model P04908: TM-score 0.97, RMSD 0.64 Å
- 7XT7 chain c against the predicted model P04908: TM-score 0.97, RMSD 0.66 Å
- 3AZN chain G against the predicted model P04908: TM-score 0.96, RMSD 0.75 Å
- 5B2J chain G against the predicted model P04908: TM-score 0.96, RMSD 0.75 Å
- 8I17 chain D against the predicted model P04908: TM-score 0.96, RMSD 0.66 Å
- 5GXQ chain G against the predicted model P04908: TM-score 0.96, RMSD 0.76 Å
- 3X1V chain C against the predicted model P04908: TM-score 0.96, RMSD 0.79 Å
- 3W96 chain G against the predicted model P04908: TM-score 0.96, RMSD 0.76 Å
- 3AZK chain G against the predicted model P04908: TM-score 0.96, RMSD 0.76 Å
Elsewhere
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