MolNFT v2 · #151615 · protein

Crystal structure of the human GalNAc-T4 in complex with UDP, manganese and the diglycopeptide 6.

6H0B: “Crystal structure of the human GalNAc-T4 in complex with UDP, manganese and the diglycopeptide 6.”. X-ray diffraction at 1.8, 3 ligands (UDP, NGA, MN). MolNFT v2 #151615 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6H0B
Type: protein
Length: 1,051 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 1.8
Source: Homo sapiens; SYNTHETIC CONSTRUCT
UniProt: Q8N4A0
Ligands: UDP, NGA, MN

Structure

x-ray diffraction · resolution 1.8 · 3 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	515	—	Q8N4A0
B	—	protein	521	—	Q8N4A0
F	—	protein	15	—	—

Ligands and binding sites

UDP · Uridine-5'-diphosphate · ligand · chains B, F
NGA · 2-acetamido-2-deoxy-beta-D-galactopyranose · sugar · 2 copies · chains B, F
MN · Manganese (II) ion · metal · chains B
EDO · 1,2-ethanediol · additive · 36 copies · chains A, B, F
GOL · Glycerol · additive · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6H0B · Crystal structure of the human galnac-T4 in complex with udp, manganese and the… · the same entry in another collection · chain A against A, TM-score 1.00
Q8N4A0 · AlphaFold monomer V2.0 prediction for polypeptide N-acetylgalactosaminyltransferase 4… · a predicted model of the same protein · chain B against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8N4A0
Elsewhere: RCSB PDB 6H0B · PDBe 6H0B · UniProt Q8N4A0

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.