UniProt Q8N4A0
Polypeptide N-acetylgalactosaminyltransferase 4 (Q8N4A0)
Polypeptide N-acetylgalactosaminyltransferase 4 (UniProt Q8N4A0), EC 2.4.1.41: 4 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 42 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q8N4A0
- Protein
- Polypeptide N-acetylgalactosaminyltransferase 4
- EC
- 2.4.1.41
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 42 · 4 records with a druggable one
Structures
5 records of Q8N4A0 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5NQA | Crystal structure of GalNAc-T4 in complex with the monoglycopeptide 3 | x-ray diffraction | A, B | NGA | 9 (best 0.70) |
| 5NQA | Crystal structure of galnac-T4 in complex with the monoglycopeptide 3 | x-ray diffraction | A, B | NGA | 9 (best 0.70) |
| 6H0B | Crystal structure of the human GalNAc-T4 in complex with UDP, manganese and the diglycopeptide 6. | x-ray diffraction | A, B | MN, UDP, NGA | 12 (best 0.80) |
| 6H0B | Crystal structure of the human galnac-T4 in complex with udp, manganese and the diglycopeptide 6. | x-ray diffraction | A, B | MN, UDP, NGA | 12 (best 0.80) |
| Q8N4A0 | AlphaFold monomer V2.0 prediction for polypeptide N-acetylgalactosaminyltransferase 4 (Q8N4A0) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6H0B chain B against the predicted model Q8N4A0: TM-score 0.98, RMSD 1.17 Å
- 6H0B chain B against the predicted model Q8N4A0: TM-score 0.98, RMSD 1.17 Å
- 6H0B chain A against the predicted model Q8N4A0: TM-score 0.92, RMSD 2.42 Å
- 6H0B chain A against the predicted model Q8N4A0: TM-score 0.92, RMSD 2.42 Å
- 5NQA chain A against the predicted model Q8N4A0: TM-score 0.92, RMSD 2.56 Å
- 5NQA chain A against the predicted model Q8N4A0: TM-score 0.92, RMSD 2.56 Å
- 5NQA chain B against the predicted model Q8N4A0: TM-score 0.89, RMSD 2.96 Å
- 5NQA chain B against the predicted model Q8N4A0: TM-score 0.89, RMSD 2.96 Å
Elsewhere
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