MolNFT v2 · #140421 · protein
Crystal structure of fucosylated IgG1 Fc complexed with bis-glycosylated soluble form of Fc gamma receptor IIIa
5XJE: “Crystal structure of fucosylated IgG1 Fc complexed with bis-glycosylated soluble form of Fc gamma receptor…”. X-ray diffraction at 2.4, 6 ligands (NAG, MAN, BMA). MolNFT v2 #140421 on GenesisL1: 3D structure, binding sites and…
- PDB
- 5XJE
- Type
- protein
- Length
- 577 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.4
- Source
- Homo sapiens
- UniProt
- P0DOX5, P08637
- Ligands
- NAG, MAN, BMA, FUC, GAL, CL
Structure
x-ray diffraction · resolution 2.4 · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 213 | — | P0DOX5 |
| B | — | protein | 215 | — | P0DOX5 |
| C | — | protein | 149 | — | P08637 |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 11 copies · chains A, C, B
- MAN · alpha-D-mannopyranose · sugar · 4 copies · chains A, B
- BMA · beta-D-mannopyranose · sugar · 3 copies · chains A, B
- FUC · alpha-L-fucopyranose · sugar · 3 copies · chains C
- GAL · beta-D-galactopyranose · sugar · 2 copies · chains A, B
- CL · Chloride ion · ion
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5XJE · Crystal structure of fucosylated IGG1 Fc complexed with bis- glycosylated soluble form of… · the same entry in another collection · chain A against A, TM-score 1.00
- P08637 · AlphaFold monomer V2.0 prediction for low affinity immunoglobulin gamma Fc region… · a predicted model of the same protein · chain C against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0DOX5
- Every structure of UniProt P08637
- Elsewhere: RCSB PDB 5XJE · PDBe 5XJE · UniProt P0DOX5 · UniProt P08637
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