UniProt P0DOX5
Immunoglobulin gamma-1 heavy chain (P0DOX5)
Immunoglobulin gamma-1 heavy chain (UniProt P0DOX5): 155 experimental structures on GenesisL1, 17 ligands bound, 317 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P0DOX5
- Protein
- Immunoglobulin gamma-1 heavy chain
- Experimental structures
- 155
- Predicted models
- 0
- Ligands
- 17
- Pockets
- 317 · 36 records with a druggable one
Structures
155 records of P0DOX5 in the MolNFT archive: 155 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1D5B | Unliganded mature oxy-cope catalytic antibody | x-ray diffraction | B, H | — | — |
| 1D5B | Unliganded mature oxy-cope catalytic antibody | x-ray diffraction | B, H | — | — |
| 1D5I | Unliganded germline precursor of an oxy-cope catalytic antibody | x-ray diffraction | H | — | — |
| 1D5I | Unliganded germline precursor of an oxy-cope catalytic antibody | x-ray diffraction | H | — | — |
| 1D6V | Conformation effects in biological catalysis introduced by oxy-cope antibody maturation | x-ray diffraction | H | — | — |
| 1D6V | Conformation effects in biological catalysis introduced by oxy-cope antibody maturation | x-ray diffraction | H | — | — |
| 1HZH | Crystal structure of the intact human IgG B12 with broad and potent activity against primary HIV-1… | x-ray diffraction | H, K | — | — |
| 1HZH | Crystal structure of the intact human IgG B12 with broad and potent activity against primary HIV-1… | x-ray diffraction | H, K | — | — |
| 1N0X | Crystal Structure of a Broadly Neutralizing Anti-HIV-1 Antibody in Complex with a Peptide Mimotope | x-ray diffraction | H, K | — | — |
| 1N0X | Crystal structure of a broadly neutralizing anti-HIV-1 antibody in complex with a peptide mimotope | x-ray diffraction | H, K | — | — |
| 3PGF | Crystal structure of maltose bound MBP with a conformationally specific synthetic antigen binder… | x-ray diffraction | H | — | — |
| 3PGF | Crystal structure of maltose bound mbp with a conformationally specific synthetic antigen binder… | x-ray diffraction | H | — | — |
| 4R26 | Crystal structure of human Fab PGT124, a broadly neutralizing and potent HIV-1 neutralizing antibody | x-ray diffraction | H | — | — |
| 4R26 | Crystal structure of human Fab PGT124, a broadly neutralizing and potent HIV-1 neutralizing antibody | x-ray diffraction | H | — | — |
| 4R2G | Crystal Structure of PGT124 Fab bound to HIV-1 JRCSF gp120 core and to CD4 | x-ray diffraction | Q, D, J, N | — | — |
| 4R2G | Crystal structure of PGT124 Fab bound to HIV-1 jrcsf GP120 core and to CD4 | x-ray diffraction | Q, D, J, N | — | — |
| 5O4E | Crystal structure of VEGF in complex with heterodimeric Fcab JanusCT6 | x-ray diffraction | A, B, C, D | NAG, BMA, MAN, FUC | 6 (best 0.51) |
| 5O4E | Crystal structure of VEGF in complex with heterodimeric fcab JANUSCT6 | x-ray diffraction | A, B, C, D | NAG, BMA, MAN | — |
| 5VJ6 | BG505 SOSIP.664 in complex with broadly neutralizing antibodies PG9 and 8ANC195 | electron microscopy | H | — | 4 (best 0.71) |
| 5VJ6 | BG505 SOSIP.664 in complex with broadly neutralizing antibodies PG9 and 8ANC195 | electron microscopy | H | — | — |
| 5VU0 | Crystal structure of the complex between afucosylated/galactosylated human IgG1 Fc and Fc gamma… | x-ray diffraction | A, B | NAG, BMA, MAN, GAL, NA | 4 (best 0.34) |
| 5VU0 | Crystal structure of the complex between AFUCOSYLATED/GALACTOSYLATED human IGG1 Fc and Fc gamma… | x-ray diffraction | A, B | NAG, BMA, MAN, GAL, NA | — |
| 5VZX | Crystal structure of crenezumab Fab | x-ray diffraction | H, E | SO4 | 10 (best 0.78) |
| 5VZX | Crystal structure of crenezumab Fab | x-ray diffraction | H, E | SO4 | — |
| 5VZY | Crystal structure of crenezumab Fab in complex with Abeta | x-ray diffraction | H | — | 4 (best 0.50) |
| 5VZY | Crystal structure of crenezumab Fab in complex with abeta | x-ray diffraction | H | — | — |
| 5W5L | Crystal structure of human IgG1-Sigma Fc fragment | x-ray diffraction | A, B | NAG, BMA, MAN, GAL, FUC | 1 (best 0.43) |
| 5W5L | Crystal structure of human IGG1-sigma Fc fragment | x-ray diffraction | A, B | NAG, BMA, MAN, GAL, FUC | — |
| 5WAV | Fc AbVance: Increasing our knowledge of antibody structural space to enable faster and better… | x-ray diffraction | A, B | NAG, MAN, FUC | 1 (best 0.27) |
| 5WAV | Fc abvance: increasing our knowledge of antibody structural space to enable faster and better… | x-ray diffraction | A, B | NAG, MAN, FUC | — |
| 5XJE | Crystal structure of fucosylated IgG1 Fc complexed with bis-glycosylated soluble form of Fc gamma… | x-ray diffraction | A, B | NAG, BMA, MAN, GAL | — |
| 5XJE | Crystal structure of fucosylated IGG1 Fc complexed with bis- glycosylated soluble form of Fc gamma… | x-ray diffraction | A, B | NAG, BMA, MAN, GAL | — |
| 5XJF | Crystal structure of fucosylated IgG Fc Y296W mutant complexed with bis-glycosylated soluble form… | x-ray diffraction | A, B | NAG, BMA, MAN, GAL, FUC, CL | 4 (best 0.46) |
| 5XJF | Crystal structure of fucosylated IgG Fc Y296W mutant complexed with bis-glycosylated soluble form… | x-ray diffraction | A, B | NAG, BMA, MAN, GAL, FUC | — |
| 5XMH | Crystal structure of an IgM rheumatoid factor YES8c in complex with IgG1 Fc | x-ray diffraction | A, B | NAG, BMA, MAN, FUC | 5 (best 0.63) |
| 5XMH | Crystal structure of an IgM rheumatoid factor YES8C in complex with IGG1 Fc | x-ray diffraction | A, B | NAG, BMA, MAN, FUC | — |
| 5Y56 | Fc mutant (K392D/K409D/D399K) | x-ray diffraction | A, B | NAG, BMA, MAN, NDG, GAL, FUL | 1 (best 0.25) |
| 5Y56 | Fc mutant (K392D/K409D/D399K) | x-ray diffraction | A, B | NAG, BMA, NDG, GAL, FUL, MAN | — |
| 5YC5 | Crystal structure of human IgG-Fc in complex with aglycan and optimized Fc gamma receptor IIIa | x-ray diffraction | A, B | NAG, BMA, MAN, GAL, FUC, CL | 1 (best 0.31) |
| 5YC5 | Crystal structure of human IgG-Fc in complex with aglycan and optimized Fc gamma receptor iiia | x-ray diffraction | A, B | NAG, BMA, MAN, GAL, FUC, CL | — |
| 6APD | Crystal structure of RSV F bound by AM22 and the infant antibody ADI-19425 | x-ray diffraction | J, K, N | — | — |
| 6APD | Crystal structure of rsv F bound by AM22 and the infant antibody adi- 19425 | x-ray diffraction | J, K, N | — | — |
| 6ARP | Structure of a mutant Cetuximab Fab fragment | x-ray diffraction | D, B | SO4 | 6 (best 0.65) |
| 6ARP | Structure of a mutant cetuximab Fab fragment | x-ray diffraction | D, B | SO4 | — |
| 6ARU | Structure of Cetuximab Fab mutant in complex with EGFR extracellular domain | x-ray diffraction | C | NAG | — |
| 6ARU | Structure of cetuximab Fab mutant in complex with EGFR extracellular domain | x-ray diffraction | C | NAG | — |
| 6B70 | Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB… | electron microscopy | C, E | — | 5 (best 0.69) |
| 6B70 | Cryo-EM structure of human insulin degrading enzyme in complex with Fab H11-E heavy chain, Fab… | electron microscopy | C, E | — | — |
| 6B7Z | Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11 heavy chain and FAB H11… | electron microscopy | C, E | — | 3 (best 0.82) |
| 6B7Z | Cryo-EM structure of human insulin degrading enzyme in complex with Fab H11 heavy chain and Fab H11… | electron microscopy | C, E | — | — |
| 6BF7 | Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB… | electron microscopy | C, E | — | — |
| 6BF7 | Cryo-EM structure of human insulin degrading enzyme in complex with Fab H11-E heavy chain, Fab… | electron microscopy | C, E | — | — |
| 6BF9 | Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB… | electron microscopy | C, E | — | 4 (best 0.80) |
| 6BF9 | Cryo-EM structure of human insulin degrading enzyme in complex with Fab H11-E heavy chain, Fab… | electron microscopy | C, E | — | — |
| 6BFT | Structure of Bevacizumab Fab mutant in complex with VEGF | x-ray diffraction | A, H | — | 10 (best 0.57) |
| 6BFT | Structure of bevacizumab Fab mutant in complex with VEGF | x-ray diffraction | A, H | — | — |
| 6BGT | Structure of Trastuzumab Fab mutant in complex with Her2 extracellular domain | x-ray diffraction | B | — | 6 (best 0.61) |
| 6BGT | Structure of trastuzumab Fab mutant in complex with HER2 extracellular domain | x-ray diffraction | B | — | — |
| 6BKB | Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 6a bound to broadly… | x-ray diffraction | H | NAG | — |
| 6BKB | Structure of hepatitis C virus envelope glycoprotein E2 core from genotype 6A bound to broadly… | x-ray diffraction | H | NAG | — |
95 records more on the page itself.
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 71 records
- MAN · alpha-D-mannopyranose · in 68 records
- BMA · beta-D-mannopyranose · in 62 records
- FUC · alpha-L-fucopyranose · in 43 records
- GAL · beta-D-galactopyranose · in 36 records
- CL · Chloride ion · in 10 records
- FUL · beta-L-fucopyranose · in 8 records
- SO4 · Sulfate ion · in 6 records
- ZN · Zinc ion · in 6 records
- K · Potassium ion · in 2 records
- NA · Sodium ion · in 2 records
- NDG · 2-acetamido-2-deoxy-alpha-D-glucopyranose · in 2 records
- PO4 · Phosphate ion · in 2 records
- UNX · Unknown atom or ion · in 2 records
- AMP · Adenosine monophosphate · in 1 record
- CA · Calcium ion · in 1 record
- GUA · Glutaric acid · in 1 record
Experiment against prediction
- 8DV2 chain D against the predicted model 3SCI: TM-score 0.99, RMSD 0.87 Å
- 8DV2 chain D against the predicted model 3SCI: TM-score 0.99, RMSD 0.87 Å
- 8DV2 chain D against the predicted model 3SCJ: TM-score 0.99, RMSD 0.94 Å
- 8DV2 chain D against the predicted model 3SCJ: TM-score 0.99, RMSD 0.94 Å
- 8DV1 chain D against the predicted model 3SCI: TM-score 0.99, RMSD 0.95 Å
- 8DV1 chain D against the predicted model 3SCI: TM-score 0.99, RMSD 0.95 Å
- 8DV1 chain D against the predicted model 3SCI: TM-score 0.99, RMSD 0.96 Å
- 8DV1 chain D against the predicted model 3SCI: TM-score 0.99, RMSD 0.96 Å
- 8DV2 chain D against the predicted model 3SCK: TM-score 0.99, RMSD 1.00 Å
- 8DV2 chain D against the predicted model 3SCK: TM-score 0.99, RMSD 1.00 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.