UniProt P08637
Low affinity immunoglobulin gamma Fc region receptor III-A (P08637)
Low affinity immunoglobulin gamma Fc region receptor III-A (UniProt P08637): 24 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 12 pockets. Binding sites, druggability and experiment against…
- UniProt
- P08637
- Protein
- Low affinity immunoglobulin gamma Fc region receptor III-A
- Experimental structures
- 24
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 12 · 1 record with a druggable one
Structures
25 records of P08637 in the MolNFT archive: 24 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3AY4 | Crystal structure of nonfucosylated Fc complexed with bis-glycosylated soluble form of Fc gamma… | x-ray diffraction | C | — | — |
| 3AY4 | Crystal structure of nonfucosylated Fc complexed with bis-glycosylated soluble form of Fc gamma… | x-ray diffraction | C | — | — |
| 3SGJ | Unique carbohydrate-carbohydrate interactions are required for high affinity binding between FcgIII… | x-ray diffraction | C | — | — |
| 3SGJ | Unique carbohydrate-carbohydrate interactions are required for high affinity binding between fcgiii… | x-ray diffraction | C | — | — |
| 3SGK | Unique carbohydrate/carbohydrate interactions are required for high affinity binding of FcgIII and… | x-ray diffraction | C | — | — |
| 3SGK | Unique CARBOHYDRATE/CARBOHYDRATE interactions are required for high affinity binding of fcgiii and… | x-ray diffraction | C | — | — |
| 3WN5 | Crystal structure of asymmetrically engineered Fc variant in complex with FcgRIIIa | x-ray diffraction | C, F | — | — |
| 3WN5 | Crystal structure of asymmetrically engineered Fc variant in complex with fcgriiia | x-ray diffraction | C, F | — | — |
| 5BW7 | Crystal structure of nonfucosylated Fc Y296W mutant complexed with bis-glycosylated soluble form of… | x-ray diffraction | C | — | — |
| 5D6D | Crystal structure of GASDALIE IgG1 Fc in complex with FcgRIIIa | x-ray diffraction | C | NAG | — |
| 5D6D | Crystal structure of gasdalie IGG1 Fc in complex with fcgriiia | x-ray diffraction | C | — | — |
| 5ML9 | Cocrystal structure of Fc gamma receptor IIIa interacting with Affimer F4, a specific binding… | x-ray diffraction | A | NAG, SO4, CL | 3 (best 0.41) |
| 5ML9 | Cocrystal structure of Fc gamma receptor iiia interacting with affimer F4, a specific binding… | x-ray diffraction | A | NAG, SO4, CL | — |
| 5MN2 | Cocrystal structure of Fc gamma receptor IIIa interacting with Affimer G3, a specific binding… | x-ray diffraction | A, B | NAG | — |
| 5MN2 | Cocrystal structure of Fc gamma receptor iiia interacting with affimer G3, a specific binding… | x-ray diffraction | A, B | NAG | — |
| 5XJE | Crystal structure of fucosylated IgG1 Fc complexed with bis-glycosylated soluble form of Fc gamma… | x-ray diffraction | C | NAG, FUC | — |
| 5XJE | Crystal structure of fucosylated IGG1 Fc complexed with bis- glycosylated soluble form of Fc gamma… | x-ray diffraction | C | NAG, FUC | — |
| 5XJF | Crystal structure of fucosylated IgG Fc Y296W mutant complexed with bis-glycosylated soluble form… | x-ray diffraction | C | NAG | 2 (best 0.46) |
| 5XJF | Crystal structure of fucosylated IgG Fc Y296W mutant complexed with bis-glycosylated soluble form… | x-ray diffraction | C | NAG | — |
| 5YC5 | Crystal structure of human IgG-Fc in complex with aglycan and optimized Fc gamma receptor IIIa | x-ray diffraction | C | NAG | — |
| 5YC5 | Crystal structure of human IgG-Fc in complex with aglycan and optimized Fc gamma receptor iiia | x-ray diffraction | C | — | — |
| 7SEG | Crystal structure of the complex of CD16A bound by an anti-CD16A Fab | x-ray diffraction | D, C | NAG | 5 (best 0.68) |
| 7SEG | Crystal structure of the complex of CD16A bound by an anti-CD16A Fab | x-ray diffraction | D, C | NAG | — |
| 7URU | Crystal structure of the low affinity Fc gamma receptor IIIA variant in complex with the Fc of IgG1. | x-ray diffraction | C | NAG | 2 (best 0.36) |
| P08637 | AlphaFold monomer V2.0 prediction for low affinity immunoglobulin gamma Fc region receptor III-a… | predicted | A | — | — |
Ligands
Experiment against prediction
- 5BW7 chain C against the predicted model P08637: TM-score 0.98, RMSD 0.71 Å
- 3AY4 chain C against the predicted model P08637: TM-score 0.98, RMSD 0.74 Å
- 3AY4 chain C against the predicted model P08637: TM-score 0.98, RMSD 0.74 Å
- 5YC5 chain C against the predicted model P08637: TM-score 0.98, RMSD 0.73 Å
- 5YC5 chain C against the predicted model P08637: TM-score 0.98, RMSD 0.73 Å
- 5D6D chain C against the predicted model P08637: TM-score 0.98, RMSD 0.74 Å
- 5D6D chain C against the predicted model P08637: TM-score 0.98, RMSD 0.74 Å
- 5XJF chain C against the predicted model P08637: TM-score 0.98, RMSD 0.73 Å
- 5XJF chain C against the predicted model P08637: TM-score 0.98, RMSD 0.73 Å
- 5XJE chain C against the predicted model P08637: TM-score 0.98, RMSD 0.73 Å
Elsewhere
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