MolNFT v1 · #140482 · protein
Crystal structure of human IgG-Fc in complex with aglycan and optimized Fc gamma receptor iiia
5YC5: “Crystal structure of human IgG-Fc in complex with aglycan and optimized Fc gamma receptor iiia”. X-ray diffraction, 6 ligands (NAG, MAN, BMA). MolNFT v1 #140482 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5YC5
- Type
- protein
- Length
- 595 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P0DOX5, P08637
- Ligands
- NAG, MAN, BMA, FUC, GAL, CL
Structure
x-ray diffraction · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 211 | — | P0DOX5 |
| B | — | protein | 213 | — | P0DOX5 |
| C | — | protein | 171 | — | P08637 |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 8 copies · chains A, B
- MAN · alpha-D-mannopyranose · sugar · 4 copies · chains A, B
- BMA · beta-D-mannopyranose · sugar · 2 copies · chains A, B
- FUC · alpha-L-fucopyranose · sugar · 2 copies · chains B
- GAL · beta-D-galactopyranose · sugar · chains A
- CL · Chloride ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5YC5 · Crystal structure of human IgG-Fc in complex with aglycan and optimized Fc gamma receptor… · the same entry in another collection · chain A against A, TM-score 1.00
- P08637 · AlphaFold monomer V2.0 prediction for low affinity immunoglobulin gamma Fc region… · a predicted model of the same protein · chain C against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0DOX5
- Every structure of UniProt P08637
- Elsewhere: RCSB PDB 5YC5 · PDBe 5YC5 · UniProt P0DOX5 · UniProt P08637
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