MolNFT v2 · #127521 · protein
Structure of MDM2-MDMX-UbcH5B-ubiquitin complex
5MNJ: “Structure of MDM2-MDMX-UbcH5B-ubiquitin complex”. X-ray diffraction at 2.16, 2 ligands (ZN, SO4). MolNFT v2 #127521 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5MNJ
- Type
- protein
- Length
- 698 residues
- Chains
- 8
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.16
- Source
- Homo sapiens
- UniProt
- P62837, P0CG47, Q00987, O15151
- Ligands
- ZN, SO4
Structure
x-ray diffraction · resolution 2.16 · 7 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, E | — | protein | 146 | — | P62837 |
| B | — | protein | 75 | — | P0CG47 |
| C | — | protein | 63 | — | Q00987 |
| D | — | protein | 63 | — | O15151 |
| F | — | protein | 76 | — | P0CG47 |
| G | — | protein | 65 | — | Q00987 |
| H | — | protein | 64 | — | O15151 |
Ligands and binding sites
- ZN · Zinc ion · metal · 8 copies · chains C, D, G, H
- SO4 · Sulfate ion · ion · 2 copies · chains D, H
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5MNJ · Structure of MDM2-mdmx-UBCH5B-ubiquitin complex · the same entry in another collection · chain H against H, TM-score 1.00
- P62837 · AlphaFold monomer V2.0 prediction for ubiquitin-conjugating enzyme E2 D2 (P62837) · a predicted model of the same protein · chain A against A, TM-score 0.98
- O15151 · AlphaFold monomer V2.0 prediction for protein MDM4 (O15151) · a predicted model of the same protein · chain D against A, TM-score 0.92
- P0CG47 · AlphaFold monomer V2.0 prediction for polyubiquitin-B (P0CG47) · a predicted model of the same protein · chain F against A, TM-score 0.91
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P62837
- Every structure of UniProt P0CG47
- Every structure of UniProt Q00987
- Every structure of UniProt O15151
- Elsewhere: RCSB PDB 5MNJ · PDBe 5MNJ · UniProt P62837 · UniProt P0CG47 · UniProt Q00987 · UniProt O15151
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