UniProt P62837
Ubiquitin-conjugating enzyme E2 D2 (P62837)
Ubiquitin-conjugating enzyme E2 D2 (UniProt P62837), EC 2.3.2.23, 2.3.2.24: 92 experimental structures on GenesisL1, 7 ligands bound, 98 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P62837
- Protein
- Ubiquitin-conjugating enzyme E2 D2
- EC
- 2.3.2.23, 2.3.2.24, 2.3.2.27, 6.3.2.19
- Experimental structures
- 92
- Predicted models
- 0
- Ligands
- 7
- Pockets
- 98 · 16 records with a druggable one
Structures
92 records of P62837 in the MolNFT archive: 92 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2CLW | Crystal structure of human ubiquitin-conjugating enzyme UbcH5B | x-ray diffraction | A, B, C, D | — | — |
| 2CLW | Crystal structure of human ubiquitin-conjugating enzyme UBCH5B | x-ray diffraction | A, B, C, D | — | — |
| 2ESK | Human Ubiquitin-Conjugating Enzyme (E2) UbcH5b, wild-type | x-ray diffraction | A | — | — |
| 2ESK | Human ubiquitin-conjugating enzyme (E2) UBCH5B, wild-type | x-ray diffraction | A | — | — |
| 2ESO | Human Ubiquitin-Conjugating Enzyme (E2) UbcH5b mutant Ile37Ala | x-ray diffraction | A | — | — |
| 2ESO | Human ubiquitin-conjugating enzyme (E2) UBCH5B mutant ILE37ALA | x-ray diffraction | A | — | — |
| 2ESP | Human ubiquitin-conjugating enzyme (E2) UbcH5b mutant Ile88Ala | x-ray diffraction | A | — | — |
| 2ESP | Human ubiquitin-conjugating enzyme (E2) UBCH5B mutant ILE88ALA | x-ray diffraction | A | — | — |
| 2ESQ | Human Ubiquitin-Conjugating Enzyme (E2) UbcH5b mutant Ser94Gly | x-ray diffraction | A | — | — |
| 2ESQ | Human ubiquitin-conjugating enzyme (E2) UBCH5B mutant SER94GLY | x-ray diffraction | A | — | — |
| 3A33 | UbcH5b~Ubiquitin Conjugate | x-ray diffraction | A | — | — |
| 3A33 | UBCH5B~UBIQUITIN conjugate | x-ray diffraction | A | — | — |
| 3JVZ | E2~Ubiquitin-HECT | x-ray diffraction | A, B | — | — |
| 3JVZ | E2~UBIQUITIN-hect | x-ray diffraction | A, B | — | — |
| 3JW0 | E2~Ubiquitin-HECT | x-ray diffraction | A, B | — | — |
| 3JW0 | E2~UBIQUITIN-hect | x-ray diffraction | A, B | — | — |
| 3L1Y | Crystal structure of human UBC4 E2 conjugating enzyme | x-ray diffraction | A | — | — |
| 3L1Y | Crystal structure of human UBC4 E2 conjugating enzyme | x-ray diffraction | A | — | — |
| 3TGD | Crystal structure of the human ubiquitin-conjugating enzyme (E2) UbcH5b | x-ray diffraction | A | — | — |
| 3TGD | Crystal structure of the human ubiquitin-conjugating enzyme (E2) UBCH5B | x-ray diffraction | A | — | — |
| 3ZNI | Structure of phosphoTyr363-Cbl-b - UbcH5B-Ub - ZAP-70 peptide complex | x-ray diffraction | C, G, K, O | — | — |
| 3ZNI | Structure of PHOSPHOTYR363-cbl-B - UBCH5B-ub - zap-70 peptide complex | x-ray diffraction | C, G, K, O | — | — |
| 4A49 | Structure of phosphoTyr371-c-Cbl-UbcH5B complex | x-ray diffraction | B | — | — |
| 4A49 | Structure of PHOSPHOTYR371-C-cbl-UBCH5B complex | x-ray diffraction | B | — | — |
| 4A4B | Structure of modified phosphoTyr371-c-Cbl-UbcH5B-ZAP-70 complex | x-ray diffraction | C | — | — |
| 4A4B | Structure of modified PHOSPHOTYR371-C-cbl-UBCH5B-zap-70 complex | x-ray diffraction | C | — | — |
| 4A4C | Structure of phosphoTyr371-c-Cbl-UbcH5B-ZAP-70 complex | x-ray diffraction | C | — | — |
| 4A4C | Structure of PHOSPHOTYR371-C-cbl-UBCH5B-zap-70 complex | x-ray diffraction | C | — | — |
| 4AUQ | Structure of BIRC7-UbcH5b-Ub complex. | x-ray diffraction | A, D | — | — |
| 4AUQ | Structure of BIRC7-UBCH5B-ub complex. | x-ray diffraction | A, D | — | — |
| 4DDG | Crystal structure of human OTUB1/UbcH5b~Ub/Ub | x-ray diffraction | A, B, C, J, K, L | — | — |
| 4DDG | Crystal structure of human OTUB1/UBCH5B~UB/UB | x-ray diffraction | A, B, C, J, K, L | — | — |
| 4DDI | Crystal structure of human OTUB1/UbcH5b~Ub/Ub | x-ray diffraction | A, B, C | — | — |
| 4DDI | Crystal structure of human OTUB1/UBCH5B~UB/UB | x-ray diffraction | A, B, C | — | — |
| 4LDT | The structure of h/ceOTUB1-ubiquitin aldehyde-UBCH5B~Ub | x-ray diffraction | C | — | — |
| 4LDT | The structure of H/CEOTUB1-ubiquitin aldehyde-UBCH5B~UB | x-ray diffraction | C | — | — |
| 4V3K | RNF38-UbcH5B-UB complex | x-ray diffraction | A, D | — | — |
| 4V3K | RNF38-UBCH5B-ub complex | x-ray diffraction | A, D | — | — |
| 4V3L | RNF38-UB-UbcH5B-Ub complex | x-ray diffraction | A | — | 5 (best 0.58) |
| 4V3L | RNF38-ub-UBCH5B-ub complex | x-ray diffraction | A | — | — |
| 4WZ3 | Crystal structure of the complex between LubX/LegU2/Lpp2887 U-box 1 and Homo sapiens UBE2D2 | x-ray diffraction | A | — | — |
| 4WZ3 | Crystal structure of the complex between LUBX/LEGU2/LPP2887 U-box 1 and homo sapiens UBE2D2 | x-ray diffraction | A | — | — |
| 5D0K | Structure of UbE2D2:RNF165:Ub complex | x-ray diffraction | A, D, G, J | — | 12 (best 0.67) |
| 5D0K | Structure of UBE2D2:RNF165:UB complex | x-ray diffraction | A, D, G, J | — | — |
| 5D0M | Structure of UbE2D2:RNF165:Ub complex | x-ray diffraction | A | PO4 | 3 (best 0.68) |
| 5D0M | Structure of UBE2D2:RNF165:UB complex | x-ray diffraction | A | — | — |
| 5D1K | Crystal Structure of UbcH5B in Complex with the RING-U5BR Fragment of AO7 | x-ray diffraction | A | OXL | 3 (best 0.55) |
| 5D1K | Crystal structure of UBCH5B in complex with the ring-U5BR fragment of AO7 | x-ray diffraction | A | — | — |
| 5D1L | Crystal Structure of UbcH5B in Complex with the RING-U5BR Fragment of AO7 (Y165A) | x-ray diffraction | A | OXL | — |
| 5D1L | Crystal structure of UBCH5B in complex with the ring-U5BR fragment of AO7 (Y165A) | x-ray diffraction | A | — | — |
| 5D1M | Crystal Structure of UbcH5B in Complex with the RING-U5BR Fragment of AO7 (P199A) | x-ray diffraction | A | OXL | — |
| 5D1M | Crystal structure of UBCH5B in complex with the ring-U5BR fragment of AO7 (P199A) | x-ray diffraction | A | — | — |
| 5EDV | Structure of the HOIP-RBR/UbcH5B~ubiquitin transfer complex | x-ray diffraction | C, D, I | — | 10 (best 0.85) |
| 5EDV | Structure of the hoip-RBR/UBCH5B~UBIQUITIN transfer complex | x-ray diffraction | C, D, I | — | — |
| 5MNJ | Structure of MDM2-MDMX-UbcH5B-ubiquitin complex | x-ray diffraction | A, E | — | — |
| 5MNJ | Structure of MDM2-mdmx-UBCH5B-ubiquitin complex | x-ray diffraction | A, E | — | — |
| 5ULF | Crystal Structure of a UbcH5b~Ub conjugate | x-ray diffraction | A, C | — | 4 (best 0.61) |
| 5ULF | Crystal structure of a UBCH5B~UB conjugate | x-ray diffraction | A, C | — | — |
| 5ULH | Structure of RNF165 in complex with a UbcH5b~Ub conjugate | x-ray diffraction | A | SCN | — |
| 5ULH | Structure of RNF165 in complex with a UBCH5B~UB conjugate | x-ray diffraction | A | SCN | — |
32 records more on the page itself.
Ligands
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.