MolNFT v2 · #119490 · protein
Crystal structure of the C. elegans Protein O-fucosyltransferase 2 (CePOFUT2) double mutant (R298K-R299K) in complex with GDP and the human TSR1 from thrombospondin 1
5FOE: “Crystal structure of the C. elegans Protein O-fucosyltransferase 2 (CePOFUT2) double mutant (R298K-R299K) in…”. X-ray diffraction at 1.98, 2 ligands (GDP, NAG). MolNFT v2 #119490 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 5FOE
- Type
- protein
- Length
- 864 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.98
- Source
- Caenorhabditis elegans; Homo sapiens
- UniProt
- Q8WR51, P07996
- Ligands
- GDP, NAG
Structure
x-ray diffraction · resolution 1.98 · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 429 | — | Q8WR51, P07996 |
| B | — | protein | 435 | — | Q8WR51, P07996 |
Ligands and binding sites
- GDP · Guanosine-5'-diphosphate · ligand · 2 copies · chains A, B
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 2 copies · chains A, B
- EDO · 1,2-ethanediol · additive · 10 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5FOE · Crystal structure of the C. elegans protein O-fucosyltransferase 2 (CEPOFUT2) double… · the same entry in another collection · chain A against A, TM-score 1.00
- Q8WR51 · AlphaFold monomer V2.0 prediction for GDP-fucose protein O-fucosyltransferase 2 (Q8WR51) · a predicted model of the same protein · chain B against A, TM-score 0.88
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8WR51
- Every structure of UniProt P07996
- Elsewhere: RCSB PDB 5FOE · PDBe 5FOE · UniProt Q8WR51 · UniProt P07996
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