MolNFT v1 · #79238 · protein
Crystal structure of BBBB+UDP+GAL with glycerol as the cryoprotectant
3SXC · Histo-blood group abo system transferase: “Crystal structure of BBBB+UDP+GAL with glycerol as the cryoprotectant”. X-ray diffraction, 3 ligands (UDP, GAL, MN), 2 pockets (best druggability 0.48). MolNFT v1 #79238 on GenesisL1: 3D…
- PDB
- 3SXC
- Type
- protein
- Length
- 275 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Histo-blood group abo system transferase
- EC
- 2.4.1.37
- UniProt
- P16442
- Ligands
- UDP, GAL, MN
- Pockets
- 2 · best druggability 0.48
Structure
x-ray diffraction · 1 distinct chain · 31% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Histo-blood group abo system transferase (EC 2.4.1.37) | protein | 275 | 31% helix, 20% strand | P16442 |
Ligands and binding sites
- UDP · Uridine-5'-diphosphate · ligand · chains A
- GAL · beta-D-galactopyranose · sugar · chains A
- MN · Manganese (II) ion · metal · chains A
- PEG · Di(hydroxyethyl)ether · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 178 | 0.48 | 0.76 | 28 | GAL, MN |
| 2 | 124 | 0.39 | 0.74 | 15 | UDP |
Compared structures
- 3SXC · Crystal structure of BBBB+UDP+Gal with Glycerol as the cryoprotectant · the same entry in another collection · chain A against A, TM-score 1.00
- P16442 · AlphaFold monomer V2.0 prediction for histo-blood group abo system transferase (P16442) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P16442
- Elsewhere: RCSB PDB 3SXC · PDBe 3SXC · UniProt P16442
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.