MolNFT v1 · #46571 · protein + DNA
Human mutsalpha (MSH2/MSH6) bound to a G T mispair, with ADP bound to MSH2 only
2O8E: “Human mutsalpha (MSH2/MSH6) bound to a G T mispair, with ADP bound to MSH2 only”. X-ray diffraction. MolNFT v1 #46571 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2O8E
- Type
- protein + DNA
- Length
- 1,789 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P43246, P52701
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| E | — | dna | 15 | — | — |
| F | — | dna | 15 | — | — |
| A | — | protein | 824 | — | P43246 |
| B | — | protein | 935 | — | P52701 |
Compared structures
- 2O8E · human MutSalpha (MSH2/MSH6) bound to a G T mispair, with ADP bound to MSH2 only · the same entry in another collection · chain E against E, TM-score 1.00
- P52701 · AlphaFold monomer V2.0 prediction for DNA mismatch repair protein MSH6 (P52701) · a predicted model of the same protein · chain B against A, TM-score 0.98
- P43246 · AlphaFold monomer V2.0 prediction for DNA mismatch repair protein MSH2 (P43246) · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P43246
- Every structure of UniProt P52701
- Elsewhere: RCSB PDB 2O8E · PDBe 2O8E · UniProt P43246 · UniProt P52701
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