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UniProt P52701

DNA mismatch repair protein Msh6 (P52701)

DNA mismatch repair protein Msh6 (UniProt P52701): 16 experimental structures on GenesisL1, 3 ligands bound, 16 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
P52701
Protein
DNA mismatch repair protein Msh6
Experimental structures
16
Predicted models
0
Ligands
3
Pockets
16 · 1 record with a druggable one

Structures

16 records of P52701 in the MolNFT archive: 16 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
2GFUNMR solution structure of the PWWP domain of Mismatch repair protein hMSH6solution nmrA——
2GFUNMR solution structure of the pwwp domain of mismatch repair protein HMSH6solution nmrA——
2O8Bhuman MutSalpha (MSH2/MSH6) bound to ADP and a G T mispairx-ray diffractionB——
2O8BHuman mutsalpha (MSH2/MSH6) bound to ADP and a G T mispairx-ray diffractionB——
2O8Chuman MutSalpha (MSH2/MSH6) bound to ADP and an O6-methyl-guanine T mispairx-ray diffractionB——
2O8CHuman mutsalpha (MSH2/MSH6) bound to ADP and an O6-methyl-guanine T mispairx-ray diffractionB——
2O8Dhuman MutSalpha (MSH2/MSH6) bound to ADP and a G dU mispairx-ray diffractionB——
2O8DHuman mutsalpha (MSH2/MSH6) bound to ADP and a G du mispairx-ray diffractionB——
2O8Ehuman MutSalpha (MSH2/MSH6) bound to a G T mispair, with ADP bound to MSH2 onlyx-ray diffractionB——
2O8EHuman mutsalpha (MSH2/MSH6) bound to a G T mispair, with ADP bound to MSH2 onlyx-ray diffractionB——
2O8Fhuman MutSalpha (MSH2/MSH6) bound to DNA with a single base T insertx-ray diffractionB——
2O8FHuman mutsalpha (MSH2/MSH6) bound to DNA with a single base T insertx-ray diffractionB——
6OQMcrystal structure of the MSH6 PWWP domainx-ray diffractionAUNX, MG, SO4—
6OQMCrystal structure of the MSH6 pwwp domainx-ray diffractionAUNX, MG, SO4—
8AG6human MutSalpha (MSH2/MSH6) binding to DNA with a GT mismatchelectron microscopyB—16 (best 0.81)
P52701AlphaFold monomer V2.0 prediction for DNA mismatch repair protein MSH6 (P52701)———

Ligands

  • MG · Magnesium ion · in 2 records
  • SO4 · Sulfate ion · in 2 records
  • UNX · Unknown atom or ion · in 2 records

Elsewhere

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