Porcine pancreatic elastase complexed with beta-casomorphin-7 and asp- phe at pH 5.0

Structure

x-ray diffraction · 2 distinct chains · 11% helix, 39% strand (DSSP).

Ligands and binding sites

• ASP · Aspartic acid · ligand · chains P, A
• PHE · Phenylalanine · ligand · chains A
• CA · Calcium ion · metal · chains A
• SO4 · Sulfate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

• P–A · 228 Ų buried · 6 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 disulfide, 1 covalent (disulfide, covalent ligand).

Compared structures

• 2BB4 · Porcine pancreatic elastase complexed with beta-casomorphin-7 and Asp-Phe at pH 5.0 · the same entry in another collection · chain P against P, TM-score 1.00
• P00772 · AlphaFold monomer V2.0 prediction for chymotrypsin-like elastase family member 1 (P00772) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P00772
• Elsewhere: RCSB PDB 2BB4 · PDBe 2BB4 · UniProt P00772