MolNFT v1 · #29150 · protein

Gppnhp-bound YPT1P GTPase

1YZN · GTP-binding protein YPT1: “Gppnhp-bound YPT1P GTPase”. X-ray diffraction, 2 ligands (GNP, MG), 1 pocket (best druggability 0.57). MolNFT v1 #29150 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1YZN
Type: protein
Length: 178 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: GTP-binding protein YPT1
UniProt: P01123
Ligands: GNP, MG
Pockets: 1 · best druggability 0.57

Structure

x-ray diffraction · 1 distinct chain · 34% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	GTP-binding protein YPT1	protein	178	34% helix, 25% strand	P01123

Ligands and binding sites

GNP · Phosphoaminophosphonic acid-guanylate ester · ligand · chains A
MG · Magnesium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	171	0.57	0.81	33	MG, GNP

Compared structures

1YZN · GppNHp-Bound Ypt1p GTPase · the same entry in another collection · chain A against A, TM-score 1.00
P01123 · AlphaFold monomer V2.0 prediction for GTP-binding protein YPT1 (P01123) · a predicted model of the same protein · chain A against A, TM-score 0.92

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P01123
Elsewhere: RCSB PDB 1YZN · PDBe 1YZN · UniProt P01123

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.