MolNFT v1 · #190708 · protein
Complex of integrin ALPHAV/BETA8 and L-TGF-BETA1 at a ratio of 1:2
7Y1T: “Complex of integrin ALPHAV/BETA8 and L-TGF-BETA1 at a ratio of 1:2”. Electron microscopy, 5 ligands (NAG, MAN, BMA). MolNFT v1 #190708 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7Y1T
- Type
- protein
- Length
- 1,030 residues
- Chains
- 3
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P06756, P26012, P01137
- Ligands
- NAG, MAN, BMA, CA, MN
Structure
electron microscopy · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 534 | — | P06756 |
| B | — | protein | 345 | — | P26012 |
| D | — | protein | 151 | — | P01137 |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 14 copies · chains B, A, D
- MAN · alpha-D-mannopyranose · sugar · 3 copies
- BMA · beta-D-mannopyranose · sugar · chains A
- CA · Calcium ion · metal · 5 copies · chains A, B
- MN · Manganese (II) ion · metal · chains B, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7Y1T · Complex of integrin alphaV/beta8 and L-TGF-beta1 at a ratio of 1:2 · the same entry in another collection · chain A against A, TM-score 1.00
- P06756 · AlphaFold monomer V2.0 prediction for integrin alpha-V (P06756) · a predicted model of the same protein · chain A against A, TM-score 0.98
- P26012 · AlphaFold monomer V2.0 prediction for integrin beta-8 (P26012) · a predicted model of the same protein · chain B against A, TM-score 0.98
- P01137 · AlphaFold monomer V2.0 prediction for transforming growth factor beta-1 proprotein… · a predicted model of the same protein · chain D against A, TM-score 0.87
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P06756
- Every structure of UniProt P26012
- Every structure of UniProt P01137
- Elsewhere: RCSB PDB 7Y1T · PDBe 7Y1T · UniProt P06756 · UniProt P26012 · UniProt P01137
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