MolNFT v1 · #190649 · protein
Structure of human excitatory amino acid transporter 2 (EAAT2) in complex with glutamate
7XR4: “Structure of human excitatory amino acid transporter 2 (EAAT2) in complex with glutamate”. Electron microscopy, 2 ligands (PC1, Y01). MolNFT v1 #190649 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7XR4
- Type
- protein
- Length
- 1,278 residues
- Chains
- 3
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P43004
- Ligands
- PC1, Y01
Structure
electron microscopy · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C | — | protein | 426 | — | P43004 |
Ligands and binding sites
- PC1 · 1,2-diacyl-sn-glycero-3-phosphocholine · ligand · 24 copies · chains A, B, C
- Y01 · Cholesterol hemisuccinate · ligand · 3 copies · chains A, B, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7XR4 · Structure of human excitatory amino acid transporter 2 (EAAT2) in complex with glutamate · the same entry in another collection · chain A against A, TM-score 1.00
- P43004 · AlphaFold monomer V2.0 prediction for excitatory amino acid transporter 2 (P43004) · a predicted model of the same protein · chain B against A, TM-score 0.63
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P43004
- Elsewhere: RCSB PDB 7XR4 · PDBe 7XR4 · UniProt P43004
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