Cryoem structure of somatostatin receptor 4 (SSTR4) with GI1 and J- 2156

Structure

electron microscopy · 5 distinct chains.

Ligands and binding sites

• I8B · (2~{S})-2-[[(2~{S})-4-azanyl-2-[(4-methylnaphthalen-1-yl)sulfonylamino]butanoyl]amino]-3-phenyl-propanimidic acid · ligand · chains R

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 7XMT · CryoEM structure of somatostatin receptor 4 (SSTR4) with Gi1 and J-2156 · the same entry in another collection · chain S against S, TM-score 1.00
• P62873 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(T)… · a predicted model of the same protein · chain B against A, TM-score 0.99
• P31391 · AlphaFold monomer V2.0 prediction for somatostatin receptor type 4 (P31391) · a predicted model of the same protein · chain R against A, TM-score 0.89
• P63096 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I) subunit… · a predicted model of the same protein · chain A against A, TM-score 0.83
• P59768 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(O)… · a predicted model of the same protein · chain C against A, TM-score 0.71

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P31391
• Every structure of UniProt P63096
• Every structure of UniProt P59768
• Every structure of UniProt P62873
• Elsewhere: RCSB PDB 7XMT · PDBe 7XMT · UniProt P31391 · UniProt P63096 · UniProt P59768 · UniProt P62873