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MolNFT v1 · #190277 · protein

Mouse TRPM8 in lipid nanodiscs in the presence of calcium and icilin

7WRE: “Mouse TRPM8 in lipid nanodiscs in the presence of calcium and icilin”. Electron microscopy, 2 ligands (KX7, CA). MolNFT v1 #190277 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
7WRE
Type
protein
Length
3,720 residues
Chains
4
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
Q8R4D5
Ligands
KX7, CA

Structure

electron microscopy · 1 distinct chain.

ChainMoleculeTypeResiduesSecondary structureUniProt
A, B, C, D—protein930—Q8R4D5

Ligands and binding sites

  • KX7 · Icilin · ligand · 4 copies · chains A, B, C, D
  • CA · Calcium ion · metal · 4 copies · chains A, B, C, D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7WRE · Mouse TRPM8 in lipid nanodiscs in the presence of calcium and icilin · the same entry in another collection · chain A against A, TM-score 1.00
  • Q8R4D5 · AlphaFold monomer V2.0 prediction for transient receptor potential cation channel… · a predicted model of the same protein · chain A against A, TM-score 0.89

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