MolNFT v1 · #190128 · protein

Cryo-EM structure of inactive MGLU3 bound to LY341495

7WI8: “Cryo-EM structure of inactive MGLU3 bound to LY341495”. Electron microscopy, 2 ligands (Z99, NAG). MolNFT v1 #190128 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7WI8
Type: protein
Length: 1,446 residues
Chains: 2
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q14832
Ligands: Z99, NAG

Structure

electron microscopy · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	—	protein	723	—	Q14832

Ligands and binding sites

Z99 · 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine · ligand · 2 copies · chains A, B
NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7WI8 · Cryo-EM structure of inactive mGlu3 bound to LY341495 · the same entry in another collection · chain A against A, TM-score 1.00
Q14832 · AlphaFold monomer V2.0 prediction for metabotropic glutamate receptor 3 (Q14832) · a predicted model of the same protein · chain B against A, TM-score 0.82

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q14832
Elsewhere: RCSB PDB 7WI8 · PDBe 7WI8 · UniProt Q14832

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