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MolNFT v1 · #190087 · protein

Sodium channel III

7WFR: “Sodium channel III”. Electron microscopy, 5 ligands (LPE, PCW, CLR). MolNFT v1 #190087 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
7WFR
Type
protein
Length
1,101 residues
Chains
1
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
Q9Y5Y9
Ligands
LPE, PCW, CLR, 95T, NAG

Structure

electron microscopy · 1 distinct chain.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein1101—Q9Y5Y9

Ligands and binding sites

  • LPE · 1-O-octadecyl-sn-glycero-3-phosphocholine · ligand · 12 copies · chains A
  • PCW · 1,2-dioleoyl-sn-glycero-3-phosphocholine · ligand · 7 copies · chains A
  • CLR · Cholesterol · ligand · 5 copies · chains A
  • 95T · 5-(4-chlorophenyl)-~{N}-(3,5-dimethoxyphenyl)furan-2-carboxamide · ligand · chains A
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 7 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7WFR · Human Nav1.8 with A-803467, class III · the same entry in another collection · chain A against A, TM-score 1.00
  • Q9Y5Y9 · AlphaFold monomer V2.0 prediction for sodium channel protein type 10 subunit alpha… · a predicted model of the same protein · chain A against A, TM-score 0.97

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