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MolNFT v1 · #18991 · protein

Solution structure of T-cell surface glycoprotein CD8 alpha chain and proto-oncogene tyrosine-protein kinase lck fragments

1Q69: “Solution structure of T-cell surface glycoprotein CD8 alpha chain and proto-oncogene tyrosine-protein kinase…”. Solution nmr, 1 ligand (ZN). MolNFT v1 #18991 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
1Q69
Type
protein
Length
48 residues
Chains
2
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
T-cell surface glycoprotein CD8 alpha chain; Proto-oncogene tyrosine-protein kinase lck
UniProt
P01732, P06239
Ligands
ZN

Structure

solution nmr · 2 distinct chains · 0% helix, 8% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AT-cell surface glycoprotein CD8 alpha chainprotein190% helix, 0% strandP01732
BProto-oncogene tyrosine-protein kinase lckprotein290% helix, 14% strandP06239

Ligands and binding sites

  • ZN · Zinc ion · metal · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

  • A–B · 261 Ų buried · 1 hydrogen bond · protein-protein

Compared structures

  • 1Q69 · Solution structure of T-cell surface glycoprotein CD8 alpha chain and Proto-oncogene… · the same entry in another collection · chain A against A, TM-score 1.00
  • P06239 · AlphaFold monomer V2.0 prediction for tyrosine-protein kinase lck (P06239) · a predicted model of the same protein · chain B against A, TM-score 0.34
  • P01732 · AlphaFold monomer V2.0 prediction for T-cell surface glycoprotein CD8 alpha chain (P01732) · a predicted model of the same protein · chain A against A, TM-score 0.20

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