UniProt P01732
T-cell surface glycoprotein CD8 alpha chain (P01732)
T-cell surface glycoprotein CD8 alpha chain (UniProt P01732): 14 experimental structures and 1 predicted model on GenesisL1, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P01732
- Protein
- T-cell surface glycoprotein CD8 alpha chain
- Experimental structures
- 14
- Predicted models
- 1
- Pockets
- 10 · 1 record with a druggable one
Structures
15 records of P01732 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1AKJ | Complex of the human MHC class I glycoprotein HLA-A2 and the T cell coreceptor CD8 | x-ray diffraction | D, E | — | — |
| 1AKJ | Complex of the human MHC class I glycoprotein HLA-A2 and the T cell coreceptor CD8 | x-ray diffraction | D, E | — | — |
| 1CD8 | Crystal structure of a soluble form of the human T cell co-receptor CD8 at 2.6 ångströms resolution | x-ray diffraction | A | — | — |
| 1CD8 | Crystal structure of a soluble form of the human T cell co- receptor CD8 at 2.6 ångströms resolution | x-ray diffraction | A | — | — |
| 1Q69 | Solution structure of T-cell surface glycoprotein CD8 alpha chain and Proto-oncogene… | solution nmr | A | — | — |
| 1Q69 | Solution structure of T-cell surface glycoprotein CD8 alpha chain and proto-oncogene… | solution nmr | A | — | — |
| 2HP4 | Computational design and crystal structure of an enhanced affinity mutant human CD8-alpha-alpha… | x-ray diffraction | A, B | — | — |
| 2HP4 | Computational design and crystal structure of an enhanced affinity mutant human CD8-alpha-alpha… | x-ray diffraction | A, B | — | — |
| 3QZW | Plasticity of human CD8 binding to peptide-HLA-A*2402 | x-ray diffraction | G, H, I, J | — | — |
| 3QZW | Plasticity of human CD8 binding to peptide-HLA-A*2402 | x-ray diffraction | G, H, I, J | — | — |
| 7UMG | Crystal structure of human CD8aa-MR1-Ac-6-FP complex | x-ray diffraction | C, D | — | 5 (best 0.86) |
| 7UMG | Crystal structure of human CD8AA-MR1-ac-6-fp complex | x-ray diffraction | C, D | — | — |
| 7UVF | Crystal structure of ZED8 Fab complex with CD8 alpha | x-ray diffraction | A, B | — | 5 (best 0.48) |
| 8EW6 | Anti-human CD8 VHH complex with CD8 alpha | x-ray diffraction | W | — | — |
| P01732 | AlphaFold monomer V2.0 prediction for T-cell surface glycoprotein CD8 alpha chain (P01732) | predicted | A | — | — |
Experiment against prediction
- 7UMG chain D against the predicted model P01732: TM-score 0.98, RMSD 0.62 Å
- 7UMG chain D against the predicted model P01732: TM-score 0.98, RMSD 0.62 Å
- 1AKJ chain D against the predicted model P01732: TM-score 0.97, RMSD 0.76 Å
- 1AKJ chain D against the predicted model P01732: TM-score 0.97, RMSD 0.76 Å
- 3QZW chain I against the predicted model P01732: TM-score 0.97, RMSD 0.75 Å
- 3QZW chain I against the predicted model P01732: TM-score 0.97, RMSD 0.75 Å
- 2HP4 chain A against the predicted model P01732: TM-score 0.97, RMSD 0.77 Å
- 2HP4 chain A against the predicted model P01732: TM-score 0.97, RMSD 0.77 Å
- 1AKJ chain E against the predicted model P01732: TM-score 0.97, RMSD 0.80 Å
- 2HP4 chain B against the predicted model P01732: TM-score 0.97, RMSD 0.77 Å
Elsewhere
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