MolNFT v1 · #189693 · protein
Inward-facing structure of human EAAT2 in the substrate-free state
7VR8: “Inward-facing structure of human EAAT2 in the substrate-free state”. Electron microscopy, 3 ligands (PC1, 9Z9, CLR). MolNFT v1 #189693 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7VR8
- Type
- protein
- Length
- 402 residues
- Chains
- 1
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P43004
- Ligands
- PC1, 9Z9, CLR
Structure
electron microscopy · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 402 | — | P43004 |
Ligands and binding sites
- PC1 · 1,2-diacyl-sn-glycero-3-phosphocholine · ligand · 2 copies · chains A
- 9Z9 · (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en · ligand · chains A
- CLR · Cholesterol · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7VR8 · Inward-facing structure of human EAAT2 in the substrate-free state · the same entry in another collection · chain A against A, TM-score 1.00
- P43004 · AlphaFold monomer V2.0 prediction for excitatory amino acid transporter 2 (P43004) · a predicted model of the same protein · chain A against A, TM-score 0.63
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P43004
- Elsewhere: RCSB PDB 7VR8 · PDBe 7VR8 · UniProt P43004
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