MolNFT v1 · #188388 · protein
Integrin ALAPHIIBBETA3 complex with EF5154
7TPD: “Integrin ALAPHIIBBETA3 complex with EF5154”. X-ray diffraction, 6 ligands (IR7, NAG, BMA). MolNFT v1 #188388 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7TPD
- Type
- protein
- Length
- 2,705 residues
- Chains
- 8
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P08514, P05106
- Ligands
- IR7, NAG, BMA, CA, MG, SO4
Structure
x-ray diffraction · 7 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 457 | — | P08514 |
| B | — | protein | 466 | — | P05106 |
| C | — | protein | 453 | — | P08514 |
| D | — | protein | 471 | — | P05106 |
| E | — | protein | 214 | — | — |
| F, L | — | protein | 214 | — | — |
| H | — | protein | 216 | — | — |
Ligands and binding sites
- IR7 · (4-{[2-oxo-4-(piperidin-4-yl)piperazin-1-yl]acetyl}phenoxy)acetic acid · ligand · 2 copies · chains A, B, C, D
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 10 copies · chains A, B, C, D
- BMA · beta-D-mannopyranose · sugar · 5 copies · chains A, C
- CA · Calcium ion · metal · 12 copies · chains A, B, C, D
- MG · Magnesium ion · metal · 2 copies · chains B, D
- SO4 · Sulfate ion · ion · 5 copies · chains A, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7TPD · Integrin alpha IIB beta3 complex with EF5154 · the same entry in another collection · chain E against E, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P08514
- Every structure of UniProt P05106
- Elsewhere: RCSB PDB 7TPD · PDBe 7TPD · UniProt P08514 · UniProt P05106
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