MolNFT v1 · #188223 · protein
Integrin ALAPHIIBBETA3 complex with eptifibatide
7THO: “Integrin ALAPHIIBBETA3 complex with eptifibatide”. X-ray diffraction, 7 ligands (MPT, NAG, BMA). MolNFT v1 #188223 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7THO
- Type
- protein
- Length
- 2,714 residues
- Chains
- 10
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P08514, P05106
- Ligands
- MPT, NAG, BMA, CA, MG, SO4, NH2
Structure
x-ray diffraction · 8 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 454 | — | P08514 |
| B | — | protein | 466 | — | P05106 |
| C | — | protein | 453 | — | P08514 |
| D | — | protein | 471 | — | P05106 |
| E | — | protein | 214 | — | — |
| F, L | — | protein | 214 | — | — |
| H | — | protein | 216 | — | — |
| M, N | — | protein | 6 | — | — |
Ligands and binding sites
- MPT · Beta-mercaptopropionic acid · ligand · 2 copies · chains D, M, N
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 10 copies · chains A, B, C, D
- BMA · beta-D-mannopyranose · sugar · 3 copies · chains A
- CA · Calcium ion · metal · 12 copies · chains A, B, C, D
- MG · Magnesium ion · metal · 2 copies · chains B, M, D, N
- SO4 · Sulfate ion · ion · 4 copies · chains A, C, L
- NH2 · Amino group · ion · 2 copies · chains D, M, N
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7THO · Integrin alpha IIB beta3 complex with Eptifibatide · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P08514
- Every structure of UniProt P05106
- Elsewhere: RCSB PDB 7THO · PDBe 7THO · UniProt P08514 · UniProt P05106
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