MolNFT v1 · #186687 · protein

Solution NMR structure of PDLIM7 PDZ bound to SNX17 peptide

7RM8 · Isoform 4 of PDZ and lim domain protein 7,SORTING nexin-17…: “Solution NMR structure of PDLIM7 PDZ bound to SNX17 peptide”. Solution nmr, 1 pocket (best druggability 0.28). MolNFT v1 #186687 on GenesisL1: 3D structure, binding sites…

PDB: 7RM8
Type: protein
Length: 110 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Isoform 4 of PDZ and lim domain protein 7,SORTING nexin-17 fusion
UniProt: Q9NR12, Q15036
Pockets: 1 · best druggability 0.28

Structure

solution nmr · 1 distinct chain · 19% helix, 30% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Isoform 4 of PDZ and lim domain protein 7,SORTING nexin-17 fusion	protein	110	19% helix, 30% strand	Q9NR12, Q15036

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	51	0.28	0.74	14	empty

Compared structures

7RM8 · Solution NMR structure of PDLIM7 PDZ bound to SNX17 peptide · the same entry in another collection · chain A against A, TM-score 1.00
Q9NR12 · AlphaFold monomer V2.0 prediction for PDZ and lim domain protein 7 (Q9NR12) · a predicted model of the same protein · chain A against A, TM-score 0.76
Q15036 · AlphaFold monomer V2.0 prediction for sorting nexin-17 (Q15036) · a predicted model of the same protein · chain A against A, TM-score 0.38

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9NR12
Every structure of UniProt Q15036
Elsewhere: RCSB PDB 7RM8 · PDBe 7RM8 · UniProt Q9NR12 · UniProt Q15036

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