UniProt Q9NR12

Isoform 4 of PDZ and LIM domain protein 7,Sorting nexin-17 fusion (Q9NR12)

Isoform 4 of PDZ and LIM domain protein 7,Sorting nexin-17 fusion (UniProt Q9NR12): 4 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score)…

UniProt: Q9NR12
Protein: Isoform 4 of PDZ and LIM domain protein 7,Sorting nexin-17 fusion
Experimental structures: 4
Predicted models: 1
Pockets: 3 · 1 record with a druggable one

Structures

5 records of Q9NR12 in the MolNFT archive: 4 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
2Q3G	Structure of the PDZ domain of human PDLIM7 bound to a C-terminal extension from human…	x-ray diffraction	A, B	—	—
2Q3G	Structure of the PDZ domain of human PDLIM7 bound to a C-terminal extension from human…	x-ray diffraction	A, B	—	—
7RM8	Solution NMR structure of PDLIM7 PDZ bound to SNX17 peptide	solution nmr	A	—	1 (best 0.28)
7RM8	Solution NMR structure of PDLIM7 PDZ bound to SNX17 peptide	solution nmr	A	—	—
Q9NR12	AlphaFold monomer V2.0 prediction for PDZ and lim domain protein 7 (Q9NR12)	predicted	A	—	2 (best 0.67)

Experiment against prediction

2Q3G chain B against the predicted model Q9NR12: TM-score 0.94, RMSD 1.34 Å
2Q3G chain B against the predicted model Q9NR12: TM-score 0.94, RMSD 1.34 Å
2Q3G chain A against the predicted model Q9NR12: TM-score 0.93, RMSD 1.31 Å
2Q3G chain A against the predicted model Q9NR12: TM-score 0.93, RMSD 1.31 Å
7RM8 chain A against the predicted model Q9NR12: TM-score 0.76, RMSD 2.70 Å
7RM8 chain A against the predicted model Q9NR12: TM-score 0.76, RMSD 2.70 Å
7RM8 chain A against the predicted model Q15036: TM-score 0.38, RMSD 4.64 Å
7RM8 chain A against the predicted model Q15036: TM-score 0.38, RMSD 4.64 Å

Elsewhere

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