MolNFT v1 · #431967 · protein
AlphaFold monomer V2.0 prediction for sorting nexin-17 (Q15036)
Q15036: “AlphaFold monomer V2.0 prediction for sorting nexin-17 (Q15036)”. 6 pockets (best druggability 0.78). MolNFT v1 #431967 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q15036
- Type
- protein
- Length
- 470 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x1870f7A7de043458b061e1a3A5431D8b56e790fE
- Molecule
- Sorting nexin-17
- UniProt
- Q15036
- Pockets
- 6 · best druggability 0.78
Structure
1 distinct chain · 33% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sorting nexin-17 | protein | 470 | 33% helix, 26% strand | Q15036 |
Pockets
6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 941 | 0.78 | 0.80 | 96 | empty |
| 2 | 84 | 0.40 | 0.78 | 16 | empty |
| 3 | 64 | 0.37 | 0.79 | 17 | empty |
| 4 | 75 | 0.35 | 0.76 | 12 | empty |
| 5 | 52 | 0.27 | 0.73 | 13 | empty |
Compared structures
- 4GXB · Structure of the SNX17 atypical FERM domain bound to the NPxY motif of P-selectin · an experimental structure of the same protein · chain A against A, TM-score 0.55
- 4GXB · Structure of the SNX17 atypical ferm domain bound to the npxy motif of P-selectin · an experimental structure of the same protein · chain A against A, TM-score 0.55
- 4TKN · Structure of the SNX17 FERM domain bound to the second NPxF motif of KRIT1 · an experimental structure of the same protein · chain A against C, TM-score 0.54
- 4TKN · Structure of the SNX17 ferm domain bound to the second npxf motif of KRIT1 · an experimental structure of the same protein · chain A against C, TM-score 0.54
- 3LUI · Crystal structure of the SNX17 px domain with bound sulphate · an experimental structure of the same protein · chain A against C, TM-score 0.23
- 3LUI · Crystal structure of the SNX17 PX domain with bound sulphate · an experimental structure of the same protein · chain A against C, TM-score 0.23
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q15036
- Elsewhere: UniProt Q15036 · AlphaFold DB Q15036
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