UniProt Q15036
Sorting nexin-17 (Q15036)
Sorting nexin-17 (UniProt Q15036): 10 experimental structures and 1 predicted model on GenesisL1, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q15036
- Protein
- Sorting nexin-17
- Experimental structures
- 10
- Predicted models
- 1
- Pockets
- 8 · 2 records with a druggable one
Structures
11 records of Q15036 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3FOG | Crystal structure of the PX domain of sorting nexin-17 (SNX17) | x-ray diffraction | A | — | — |
| 3FOG | Crystal structure of the px domain of sorting nexin-17 (SNX17) | x-ray diffraction | A | — | — |
| 3LUI | Crystal structure of the SNX17 PX domain with bound sulphate | x-ray diffraction | A, B, C | — | — |
| 3LUI | Crystal structure of the SNX17 px domain with bound sulphate | x-ray diffraction | A, B, C | — | — |
| 4GXB | Structure of the SNX17 atypical FERM domain bound to the NPxY motif of P-selectin | x-ray diffraction | A | — | — |
| 4GXB | Structure of the SNX17 atypical ferm domain bound to the npxy motif of P-selectin | x-ray diffraction | A | — | — |
| 4TKN | Structure of the SNX17 FERM domain bound to the second NPxF motif of KRIT1 | x-ray diffraction | A, B, C | — | — |
| 4TKN | Structure of the SNX17 ferm domain bound to the second npxf motif of KRIT1 | x-ray diffraction | A, B, C | — | — |
| 7RM8 | Solution NMR structure of PDLIM7 PDZ bound to SNX17 peptide | solution nmr | A | — | — |
| 9AU7 | Human Retriever VPS35L/VPS29/VPS26C complex bound to SNX17 peptide (Composite Map) | electron microscopy | D | — | 2 (best 0.71) |
| Q15036 | AlphaFold monomer V2.0 prediction for sorting nexin-17 (Q15036) | predicted | A | — | 6 (best 0.78) |
Experiment against prediction
- 3LUI chain B against the predicted model Q15036: TM-score 0.99, RMSD 0.43 Å
- 3LUI chain B against the predicted model Q15036: TM-score 0.99, RMSD 0.43 Å
- 4TKN chain A against the predicted model Q15036: TM-score 0.98, RMSD 0.80 Å
- 4TKN chain A against the predicted model Q15036: TM-score 0.98, RMSD 0.80 Å
- 3LUI chain A against the predicted model Q15036: TM-score 0.98, RMSD 0.49 Å
- 3LUI chain A against the predicted model Q15036: TM-score 0.98, RMSD 0.49 Å
- 4GXB chain A against the predicted model Q15036: TM-score 0.98, RMSD 0.86 Å
- 4GXB chain A against the predicted model Q15036: TM-score 0.98, RMSD 0.86 Å
- 4TKN chain B against the predicted model Q15036: TM-score 0.98, RMSD 0.99 Å
- 4TKN chain B against the predicted model Q15036: TM-score 0.98, RMSD 0.99 Å
Elsewhere
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