MolNFT v2 · #63929 · protein

Crystal structure of the PX domain of sorting nexin-17 (SNX17)

3FOG: “Crystal structure of the PX domain of sorting nexin-17 (SNX17)”. X-ray diffraction at 2.8, 1 ligand (NA), 1 pocket (best druggability 0.27). MolNFT v2 #63929 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3FOG
Type: protein
Length: 102 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 2.8
Source: Homo sapiens
Molecule: Sorting nexin-17
UniProt: Q15036
Ligands: NA
Pockets: 1 · best druggability 0.27

Structure

x-ray diffraction · resolution 2.8 · 1 distinct chain · 51% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Sorting nexin-17	protein	102	51% helix, 16% strand	Q15036

Ligands and binding sites

NA · Sodium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	55	0.27	0.74	12	NA

Compared structures

3FOG · Crystal structure of the px domain of sorting nexin-17 (SNX17) · the same entry in another collection · chain A against A, TM-score 1.00
Q15036 · AlphaFold monomer V2.0 prediction for sorting nexin-17 (Q15036) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q15036
Elsewhere: RCSB PDB 3FOG · PDBe 3FOG · UniProt Q15036

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