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MolNFT v1 · #185776 · protein

Crystal structure of a mutant (P393GX) thyroid receptor alpha ligand binding domain designed to model dominant negative human mutations.

7QDT: “Crystal structure of a mutant (P393GX) thyroid receptor alpha ligand binding domain designed to model…”. X-ray diffraction, 1 ligand (T3). MolNFT v1 #185776 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
7QDT
Type
protein
Length
236 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P10827
Ligands
T3

Structure

x-ray diffraction · 1 distinct chain.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein236—P10827

Ligands and binding sites

  • T3 · 3,5,3'triiodothyronine · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7QDT · Crystal structure of a mutant (P393GX) Thyroid Receptor Alpha ligand binding domain… · the same entry in another collection · chain A against A, TM-score 1.00
  • P10827 · AlphaFold monomer V2.0 prediction for thyroid hormone receptor alpha (P10827) · a predicted model of the same protein · chain A against A, TM-score 0.96

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