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MolNFT v1 · #183641 · protein

Crystal structure of the complex of DNase I/G-ACTIN/PPP1R15A_582-621

7NXV: “Crystal structure of the complex of DNase I/G-ACTIN/PPP1R15A_582-621”. X-ray diffraction, 3 ligands (ATP, NAG, CA). MolNFT v1 #183641 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
7NXV
Type
protein
Length
1,341 residues
Chains
6
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P68135, P00639, O75807
Ligands
ATP, NAG, CA

Structure

x-ray diffraction · 5 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein373—P68135
B, F—protein260—P00639
C—protein38—O75807
D—protein371—P68135
E—protein39—O75807

Ligands and binding sites

  • ATP · Adenosine-5'-triphosphate · ligand · 2 copies · chains A, D
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 4 copies · chains B, F
  • CA · Calcium ion · metal · 6 copies · chains B, F

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7NXV · Crystal structure of the complex of DNase I/G-actin/PPP1R15A_582-621 · the same entry in another collection · chain F against F, TM-score 1.00
  • P00639 · AlphaFold monomer V2.0 prediction for deoxyribonuclease-1 (P00639) · a predicted model of the same protein · chain B against A, TM-score 1.00
  • P68135 · AlphaFold monomer V2.0 prediction for actin, alpha skeletal muscle (P68135) · a predicted model of the same protein · chain D against A, TM-score 0.98
  • O75807 · AlphaFold monomer V2.0 prediction for protein phosphatase 1 regulatory subunit 15A… · a predicted model of the same protein · chain C against A, TM-score 0.74

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