MolNFT v1 · #182858 · protein

Structure of pppa bound human ACAT2

7N6Q: “Structure of pppa bound human ACAT2”. Electron microscopy, 3 ligands (CLR, 7T8, OLA). MolNFT v1 #182858 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7N6Q
Type: protein
Length: 1,500 residues
Chains: 4
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: O75908
Ligands: CLR, 7T8, OLA

Structure

electron microscopy · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C, D	—	protein	375	—	O75908

Ligands and binding sites

CLR · Cholesterol · ligand · 8 copies · chains A, B, C, D
7T8 · (3s,4r,4ar,6s,6as,12r,12as,12bs)-4-[(acetyloxy)methyl]-12-hydroxy-4,6A,12B-trimethyl-11-oxo-9-(pyridin-3-yl)-1,3,4,4A,5,6,6A,12,12A,12B-decahydro-2H,11H-naphtho[2, 1-b]pyrano[3,4-e]pyran-3,6-diyl diacetate · ligand · 4 copies · chains A, B, C, D
OLA · Oleic acid · ligand · 4 copies · chains A, B, C, D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7N6Q · Structure of PPPA bound human ACAT2 · the same entry in another collection · chain A against A, TM-score 1.00
O75908 · AlphaFold monomer V2.0 prediction for sterol O-acyltransferase 2 (O75908) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

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Every structure of UniProt O75908
Elsewhere: RCSB PDB 7N6Q · PDBe 7N6Q · UniProt O75908

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